Proteinase 3 (PR3)

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MBN; PRTN3; ACPA; AGP7; C-ANCA; MBT; P29; PRK; Myeloblastin; Serine Proteinase,Neutrophil,Wegener Granulomatosis Autoantigen; Protease K; Proteinase K; Endopeptidase K

Proteinase 3 (PR3)

PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.

Proteinase K is commonly used in molecular biology to digest protein and remove contamination from preparations of nucleic acid. Addition of proteinase K to nucleic acid preparations rapidly inactivates nucleases that might otherwise degrade the DNA or RNA during purification.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPB434Hu01Recombinant Proteinase 3 (PR3)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAB434Hu01Polyclonal Antibody to Proteinase 3 (PR3)WB, ICC, IHC-P, IHC-F, ELISA
MAB434Hu22Monoclonal Antibody to Proteinase 3 (PR3)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEB434HuELISA Kit for Proteinase 3 (PR3)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPB434Mu01Recombinant Proteinase 3 (PR3)SDS-PAGE; WB; ELISA; IP.
RPB434Mu02Recombinant Proteinase 3 (PR3)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAB434Mu01Polyclonal Antibody to Proteinase 3 (PR3)WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM.
LAB434Mu71Biotin-Linked Polyclonal Antibody to Proteinase 3 (PR3)IHC;WB;ELISA
PAB434Mu02Polyclonal Antibody to Proteinase 3 (PR3)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEB434MuELISA Kit for Proteinase 3 (PR3)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPB434Ra01Recombinant Proteinase 3 (PR3)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAB434Ra01Polyclonal Antibody to Proteinase 3 (PR3)WB, ICC, IHC-P, IHC-F, ELISA
LAB434Ra71Biotin-Linked Polyclonal Antibody to Proteinase 3 (PR3)IHC;WB;ELISA
MAB434Ra21Monoclonal Antibody to Proteinase 3 (PR3)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEB434RaELISA Kit for Proteinase 3 (PR3)Enzyme-linked immunosorbent assay for Antigen Detection
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