Coagulation Factor VII (F7)


FVII; SPCA; proconvertin; Cothromboplastin; Serum Prothrombin Conversation Accelerator; Stable Factor; Eptacog alfa

Coagulation Factor VII (F7)
The main role of factor VII (FVII) is to initiate the process of coagulation in conjunction with tissue factor (TF). Tissue factor is found on the outside of blood vessels - normally not exposed to the bloodstream. Upon vessel injury, tissue factor is exposed to the blood and circulating factor VII. Once bound to TF, FVII is activated to FVIIa by different proteases, among which are thrombin (factor IIa), factor Xa, IXa, XIIa, and the FVIIa-TF complex itself.
The most important substrates for FVIIa-TF are Factor X and Factor IX. The action of the factor is impeded by tissue factor pathway inhibitor (TFPI), which is released almost immediately after initiation of coagulation. Factor VII is vitamin K dependent; it is produced in the liver. Use of warfarin or similar anticoagulants impairs its function.

Organism species: Homo sapiens (Human)

ProteinsRPB874Hu01Recombinant Coagulation Factor VII (F7)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAB874Hu01Polyclonal Antibody to Coagulation Factor VII (F7)WB, ICC, IHC-P, IHC-F, ELISA
MAB874Hu22Monoclonal Antibody to Coagulation Factor VII (F7)WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM.
LAB874Hu71Biotin-Linked Polyclonal Antibody to Coagulation Factor VII (F7)IHC;WB;ELISA
Assay KitsSEB874HuELISA Kit for Coagulation Factor VII (F7)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

ProteinsRPB874Mu01Recombinant Coagulation Factor VII (F7)SDS-PAGE; WB; ELISA; IP.
RPB874Mu02Recombinant Coagulation Factor VII (F7)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAB874Mu01Polyclonal Antibody to Coagulation Factor VII (F7)WB, ICC, IHC-P, IHC-F, ELISA
LAB874Mu71Biotin-Linked Polyclonal Antibody to Coagulation Factor VII (F7)IHC;WB;ELISA
PAB874Mu02Polyclonal Antibody to Coagulation Factor VII (F7)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEB874MuELISA Kit for Coagulation Factor VII (F7)Enzyme-linked immunosorbent assay for Antigen Detection
HEB874MuHigh Sensitive ELISA Kit for Coagulation Factor VII (F7)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

ProteinsRPB874Ra01Recombinant Coagulation Factor VII (F7)SDS-PAGE; WB; ELISA; IP.
RPB874Ra02Recombinant Coagulation Factor VII (F7)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAB874Ra01Polyclonal Antibody to Coagulation Factor VII (F7)WB, ICC, IHC-P, IHC-F, ELISA
PAB874Ra02Polyclonal Antibody to Coagulation Factor VII (F7)WB, ICC, IHC-P, IHC-F, ELISA
LAB874Ra71Biotin-Linked Polyclonal Antibody to Coagulation Factor VII (F7)IHC;WB;ELISA
Assay KitsSEB874RaELISA Kit for Coagulation Factor VII (F7)Enzyme-linked immunosorbent assay for Antigen Detection
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