Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)

[Edit]

G3PD; GAPD; Peptidyl-cysteine S-nitrosylase GAPDH

Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)

Glyceraldehyde 3-phosphate dehydrogenase is an enzyme that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules. In addition to this long established metabolic function, GAPDH has recently been implicated in several non-metabolic processes, including transcription activation, initiation of apoptosis , and ER to Golgi vesicle shuttling. Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) catalyses the conversion of glyceraldehyde 3-phosphate as the name indicates. This is the 6th step of the breakdown of glucose (glycolysis), an important pathway of energy and carbon molecule supply located in the cytosol of eukaryotic cells. Glyceraldehyde 3-phosphate is converted to D-glycerate 1,3-bisphosphate in two coupled steps.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB932Hu01 Recombinant Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Positive Control; Immunogen; SDS-PAGE; WB.
RPB932Hu02 Recombinant Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Positive Control; Immunogen; SDS-PAGE; WB.
RPB932Hu03 Recombinant Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB932Hu01 Polyclonal Antibody to Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) WB; IHC; ICC; IP.
MAB932Hu22 Monoclonal Antibody to Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Loading Control of WB; IHC; ICC.
PAB932Hu02 Polyclonal Antibody to Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) WB; IHC; ICC; IP.
LAB932Hu71 Biotin-Linked Polyclonal Antibody to Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) WB; IHC; ICC.
CAB932Hu22 Anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Monoclonal Antibody Loading Control of WB.
CAB932Hu01 Anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Polyclonal Antibody Loading Control of WB.
CAB932Mi01 Anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Polyclonal Antibody Loading Control of WB.
CAB932Mi22 Anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Monoclonal Antibody Loading Control of WB
MAB932Hu21 Monoclonal Antibody to Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) WB; IHC; ICC; IP.
MAB932Hu23 Monoclonal Antibody to Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) WB; IHC; ICC; IP.
MAB932Hu24 Monoclonal Antibody to Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) WB; IHC; ICC; IP.
MAB932Hu25 Monoclonal Antibody to Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) WB; IHC; ICC; IP.
MAB932Hu27 Monoclonal Antibody to Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) WB; IHC; ICC; IP.
MAB932Hu29 Monoclonal Antibody to Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) WB; IHC; ICC; IP.
MAB932Hu26 Monoclonal Antibody to Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) WB; IHC; ICC; IP.
MAB932Hu28 Monoclonal Antibody to Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) WB; IHC; ICC; IP.
Assay Kits SEB932Hu ELISA Kit for Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Enzyme-linked immunosorbent assay for Antigen Detection.
SCB932Hu CLIA Kit for Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB932Mu01 Recombinant Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Positive Control; Immunogen; SDS-PAGE; WB.
RPB932Mu02 Recombinant Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB932Mu01 Polyclonal Antibody to Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) WB; IHC; ICC; IP.
LAB932Mu71 Biotin-Linked Polyclonal Antibody to Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) WB; IHC; ICC.
PAB932Mu02 Polyclonal Antibody to Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) WB; IHC; ICC; IP.
CAB932Mi01 Anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Polyclonal Antibody Loading Control of WB.
CAB932Mi22 Anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Monoclonal Antibody Loading Control of WB
Assay Kits SEB932Mu ELISA Kit for Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB932Ra01 Recombinant Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies CAB932Mi01 Anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Polyclonal Antibody Loading Control of WB.
CAB932Mi22 Anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Monoclonal Antibody Loading Control of WB
Assay Kits n/a CLIA Kit for Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) ELISA Kit Customized Service Offer

Organism species: Ovis aries; Ovine (Sheep)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Recombinant Protein Customized Service Offer
Antibodies PAB932Ov01 Polyclonal Antibody to Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) ELISA Kit Customized Service Offer
  1. "The glyceraldehyde 3 phosphate dehydrogenase gene family: structure of a human cDNA and of an X chromosome linked pseudogene; amazing complexity of the gene family in mouse."EMBO J. 3:2627-2633(1984) [PubMed] [Europe PMC] [Abstract]
  2. "The complete sequence of a full length cDNA for human liver glyceraldehyde-3-phosphate dehydrogenase: evidence for multiple mRNA species."Nucleic Acids Res. 12:9179-9189(1984) [PubMed] [Europe PMC] [Abstract]
  3. "Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene."Nucleic Acids Res. 13:2485-2502(1985) [PubMed] [Europe PMC] [Abstract]
  4. "Enhanced expression of a glyceraldehyde-3-phosphate dehydrogenase gene in human lung cancers."Cancer Res. 47:5616-5619(1987) [PubMed] [Europe PMC] [Abstract]
  5. "Identification of the 37-kDa protein displaying a variable interaction with the erythroid cell membrane as glyceraldehyde-3-phosphate dehydrogenase."J. Biol. Chem. 262:649-653(1987) [PubMed] [Europe PMC] [Abstract]
  6. "Isolation and complete sequence of a functional human glyceraldehyde-3-phosphate dehydrogenase gene."J. Biol. Chem. 263:15335-15341(1988) [PubMed] [Europe PMC] [Abstract]
  7. "A human nuclear uracil DNA glycosylase is the 37-kDa subunit of glyceraldehyde-3-phosphate dehydrogenase."Proc. Natl. Acad. Sci. U.S.A. 88:8460-8464(1991) [PubMed] [Europe PMC] [Abstract]
  8. "cDNA cloning by amplification of circularized first strand cDNAs reveals non-IRE-regulated iron-responsive mRNAs."Biochem. Biophys. Res. Commun. 275:223-227(2000) [PubMed] [Europe PMC] [Abstract]
  9. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  10. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  11. "The complete amino acid sequence of human muscle glyceraldehyde 3-phosphate dehydrogenase."FEBS Lett. 134:143-146(1981) [PubMed] [Europe PMC] [Abstract]
  12. "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."Nat. Biotechnol. 21:566-569(2003) [PubMed] [Europe PMC] [Abstract]