Lamin B1 (LMNB1)
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.
LMNB1 encodes a deduced 586-amino acid protein with a calculated molecular mass of 66,334 Da. The LMNB1 protein shares approximately 72% sequence similarity with lamin A/C.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF548Mi01 Recombinant Lamin B1 (LMNB1) Positive Control; Immunogen; SDS-PAGE; WB.
RPF548Hu01 Recombinant Lamin B1 (LMNB1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF548Mi01 Polyclonal Antibody to Lamin B1 (LMNB1) WB; IHC; ICC; IP.
PAF548Hu01 Polyclonal Antibody to Lamin B1 (LMNB1) WB; IHC; ICC; IP.
CAF548Hu22 Anti-Lamin B1 (LMNB1) Monoclonal Antibody Loading Control of WB
CAF548Hu01 Anti-Lamin B1 (LMNB1) Polyclonal Antibody Loading Control of WB
MAF548Hu21 Monoclonal Antibody to Lamin B1 (LMNB1) Loading Control of WB; IHC; ICC; IP.
CAF548Mi22 Anti-Lamin B1 (LMNB1) Monoclonal Antibody Loading Control of WB
Assay Kits SEF548Mi ELISA Kit for Lamin B1 (LMNB1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF548Mi01 Recombinant Lamin B1 (LMNB1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF548Mi01 Polyclonal Antibody to Lamin B1 (LMNB1) WB; IHC; ICC; IP.
PAF548Mu01 Polyclonal Antibody to Lamin B1 (LMNB1) WB; IHC; ICC; IP.
CAF548Mi22 Anti-Lamin B1 (LMNB1) Monoclonal Antibody Loading Control of WB
Assay Kits SEF548Mi ELISA Kit for Lamin B1 (LMNB1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF548Mi01 Recombinant Lamin B1 (LMNB1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF548Mi01 Polyclonal Antibody to Lamin B1 (LMNB1) WB; IHC; ICC; IP.
CAF548Mi22 Anti-Lamin B1 (LMNB1) Monoclonal Antibody Loading Control of WB
Assay Kits SEF548Mi ELISA Kit for Lamin B1 (LMNB1) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "In vitro posttranslational modification of lamin B cloned from a human T-cell line."Mol. Cell. Biol. 10:2164-2175(1990) [PubMed] [Europe PMC] [Abstract]
  2. "Structural organization of the human gene (LMNB1) encoding nuclear lamin B1."Genomics 27:230-236(1995) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]