Biotin-Linked Polyclonal Antibody to Complement 1q (C1q)

C1-q; Autoantigen Clq

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against C1q. It has been selected for its ability to recognize C1q in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
Journal of Clinical Immunology Complement activation contributes to the injury and outcome of kidney in human anti-glomerular basement membrane disease. PubMed: 22941511
Fish and Shellfish Immunology Characterization of complement 1q binding protein of tiger shrimp, Penaeus monodon, and its C1q binding activity Pubmed: 23085472
Journal of Neuroimmunology Acute and prolonged complement activation in the central nervous system during herpes simplex encephalitis Pubmed:27235358
Archives of Gynecology and Obstetrics The role of complement components C1q, MBL and C1 inhibitor in pathogenesis of endometriosis Pubmed:29572748
Journal of NeuroVirology Intrathecal complement activation by the classical pathway in tick-borne encephalitis Pubmed: 30850976
PLoS One Complement activation profile of patients with primary focal segmental glomerulosclerosis Pubmed: 32569286
CELL Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia 33248023
Chinese Journal of Nephrology, Dialysis & Transplantation Plasma and urine complement activation products in light chain and heavy chain deposition disease
Journal of Chemical Neuroanatomy Matrine treatment induced an A2 astrocyte phenotype and protected the blood-brain barrier in CNS autoimmunity 34280490
Neuropsychiatr Dis Treat Elevated Serum Complement C1q Levels After Traumatic Brain Injury and Its Association with Poor Prognosis Pubmed:35035218
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