Monoclonal Antibody to Complement Component 5a (C5a)
- Product No.MAA388Mu21
- Organism SpeciesMus musculus (Mouse) Same name, Different species.
- SourceMonoclonal antibody preparation
- Potency (Clone Number)C8
- Ig Isotype IgG2b Kappa
- PurificationProtein A + Protein G affinity chromatography
- Immunogen RPA388Mu01-Recombinant Complement Component 5a (C5a)
- Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
- Organism Species MoreHomo sapiens (Human), Rattus norvegicus (Rat)
- ApplicationsWB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
- DownloadInstruction Manual
- UOM 20µl100µl 200µl 1ml 10ml
For more details, please contact local distributors! US$ 245
For more details, please contact local distributors! US$ 350
For more details, please contact local distributors! US$ 875
For more details, please contact local distributors! US$ 3500
For more details, please contact local distributors!
The antibody is a mouse monoclonal antibody raised against C5a. It has been selected for its ability to recognize C5a in immunohistochemical staining and western blotting.
Western blotting: 0.5-2µg/mL;1:500-2000
Optimal working dilutions must be determined by end user.
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
|Molecular Immunology||Cathepsin D is released after severe tissue trauma in vivo and is capable of generating C5a in vitro ScienceDirect: S0161589011008297|
|Journal of Reproductive Immunology||Elevated complement factor C5a in maternal and umbilical cord plasma in preeclampsia PubMed: 23415845|
|The Journal of Clinical Investigation||Complement component 5 contributes to poor disease outcome in humans and mice with pneumococcal meningitis PubMed: PMC3195471|
|Journal of Antimicrobial Chemotherapy||Efficacy of a synthetic antimicrobial peptidomimetic versus vancomycin in a Staphylococcus epidermidis device-related murine peritonitis model Pubmed: 23645587|
|Journal of Orthopaedic Research||Conversion from external fixator to intramedullary nail causes a second hit and impairs fracture healing in a severe trauma model Pubmed: 23070742|
|SpringerPlus||Therapeutic effects of sesame oil on monosodium urate crystal-induced acute inflammatory response in rats Pubmed: 24353977|
|American Journal fo Reproductive Immunology||Evaluation of the Markers of Inflammation in the Umbilical Cord Blood of Newborns of Mothers with Thrombophilia Pubmed:25209155|
|Gynecol Obstet Invest||Complement Split Products C3a/C5a and Receptors: Are They Regulated by Circulating Angiotensin II Type 1 Receptor Autoantibody in Severe Preeclampsia? PubMed: 26485247|
|Journal of Neuroimmunology||Acute and prolonged complement activation in the central nervous system during herpes simplex encephalitis Pubmed:27235358|
|International Immunopharmacology||Consistency and pathophysiological characterization of a rat polymicrobial sepsis model via the improved cecal ligation and puncture surgery Pubmed:26802602|
|Digital Repository||Dosagem de frações ativadas do sistema complemento em empiema induzido em ratos 10183|
|Environmental Pollution||Cadmium-induced immune abnormality is a key pathogenic event in human and rat models of preeclampsia pubmed:27511439|
|Cancer Letters||Complement C5a/C5aR pathway potentiates the pathogenesis Q5 of gastric cancer by down-regulating p21 expression pubmed:29031586|
|Acta Paediatrica||Serum complement factor 5a levels are associated with nonalcoholic fatty liver disease in obese children DOI: 10.1111/apa.14106|
|Scientific Reports||Splenectomy modulates early immuno-inflammatory responses to trauma-hemorrhage and protects mice against secondary sepsis Pubmed: 30291296|
|Nutrients||The Beneficial Effects of Lactobacillus plantarum PS128 on High-Intensity, Exercise-Induced Oxidative Stress, Inflammation, and Performance in Triathletes Pubmed: 30736479|
|Journal of NeuroVirology||Intrathecal complement activation by the classical pathway in tick-borne encephalitis Pubmed: 30850976|
|PLoS One||Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model Pubmed: 31247004|
|Frontiers in Immunology||C5a/C5aR Pathway is Critical for the Pathogenesis of Psoriasis Pubmed: 31447855|
|Phytomedicine||Novel evidence that an alternative complement cascade pathway is involved in optimal mobilization of hematopoietic stem/progenitor cells in Nlrp3 …|
|Catalog No.||Related products for research use of Mus musculus (Mouse) Organism species||Applications (RESEARCH USE ONLY!)|
|RPA388Mu01||Recombinant Complement Component 5a (C5a)||Positive Control; Immunogen; SDS-PAGE; WB.|
|EPA388Mu61||Eukaryotic Complement Component 5a (C5a)||Positive Control; Immunogen; SDS-PAGE; WB.|
|PAA388Mu01||Polyclonal Antibody to Complement Component 5a (C5a)||WB; IHC; ICC; IP.|
|LAA388Mu71||Biotin-Linked Polyclonal Antibody to Complement Component 5a (C5a)||WB; IHC; ICC.|
|MAA388Mu21||Monoclonal Antibody to Complement Component 5a (C5a)||WB; IHC; ICC; IP.|
|LAA388Mu72||Biotin-Linked Monoclonal Antibody to Complement Component 5a (C5a)||WB; IHC; ICC.|
|SEA388Mu||ELISA Kit for Complement Component 5a (C5a)||Enzyme-linked immunosorbent assay for Antigen Detection.|
|HEA388Mu||High Sensitive ELISA Kit for Complement Component 5a (C5a)||Enzyme-linked immunosorbent assay for Antigen Detection.|
|SCA388Mu||CLIA Kit for Complement Component 5a (C5a)||Chemiluminescent immunoassay for Antigen Detection.|
|PSA388Mu01||Antibody Pair for Complement Component 5a (C5a)||ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays.|
|KSA388Mu01||ELISA Kit DIY Materials for Complement Component 5a (C5a)||Main materials for "Do It (ELISA Kit) Yourself".|