Recombinant Interferon Gamma Induced Protein 10kDa (IP10)

CXCL10; C7; IFI10; INP10; SCYB10; Crg2; GIP10; Mob1; Chemokine C-X-C Motif Ligand 10; Small Inducible Cytokine Subfamily B(Cys-X-Cys)Member 10

  • Product No.RPA371Ha01
  • Organism SpeciesHamster (Chinese hamster) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass12.4kDa
  • Accurate Molecular Mass15kDa(Analysis of differences refer to the manual)
  • Residues & TagsIle22~Ser98 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point10.9
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 200  US$ 500  US$ 1000  US$ 3000  US$ 7500 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
20 Melatonin inhibits type 1 interferon signaling of toll-like receptor 4 via heme oxygenase-1 induction in hepatic ischemia/reperfusion. PubMed: 22288937
BMC Pregnancy and Childbirth Maternal circulating leukocytes display early chemotactic responsiveness during late gestation PubMed: PMC3561147
Rheumatology International Serum levels of selected chemokines in systemic lupus erythematosus patients Pubmed: 22461186
PLOS ONE The Immunosuppressant Protosappanin A Diminished Recipient T Cell Migration into Allograft via Inhibition of IP-10 in Rat Heart Transplant Pubmed:24798458
Front Pharmacol The G-Protein-Coupled Bile Acid Receptor Gpbar1 (TGR5) Inhibits Gastric Inflammation Through Antagonizing NF-κB Signaling Pathway PubMed: 26696888
Cytokine Hypoxia/ischemia promotes CXCL10 expression in cardiac microvascular endothelial cells by NFkB activation Pubmed:26891076
Journal of Experimental & Clinical Cancer Research LPS alters the immuno-phenotype of glioma and glioma stem-like cells and induces in vivo antitumor immunity via TLR4. pubmed:28641579
Journal of Geriatric Oncology Serum biomarkers for predicting overall survival and early mortality in older patients with metastatic solid tumors Pubmed: 30952517
Hepatology Integrated Omics Reveals Tollip as an Aggravator and Therapeutic Target for Hepatic Ischemia‐Reperfusion Injury in Mice Pubmed: 31077413
Molecular Medicine Reports IL‑17A promotes CXCR2‑dependent angiogenesis in a mouse model of liver cancer Pubmed: 31173199
JOURNAL OF MOLECULAR NEUROSCIENCE Inflammatory Responses of Astrocytes Are Independent from Lipocalin 2 Pubmed: 32959226
Catalog No. Related products for research use of Hamster (Chinese hamster) Organism species Applications (RESEARCH USE ONLY!)
RPA371Ha01 Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Positive Control; Immunogen; SDS-PAGE; WB.