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Recombinant Heparan Sulfate Proteoglycan (HSPG)

SDC2; HSPG1; SYND2; Fibroglycan; Syndecan 2; Syndecan Proteoglycan 2; Heparan Sulfate Proteoglycan 1,Cell Surface-Associated; Heparan Sulphate Proteoglycan

  • Product No.RPA565Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane
  • Predicted Molecular Mass15.2kDa
  • Accurate Molecular Mass23kDa(Analysis of differences refer to the manual)
  • Residues & TagsGlu19~Glu144 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point4.7
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 144  US$ 360  US$ 720  US$ 2160  US$ 5400 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Journal of Applied Pharmaceutical Science Cytotoxic effects of antiglypican-3 against HepG3 cell line Ebscohost: Source
Journal of Reproductive Immunology Fibrinogen, an endogenous ligand of Toll-like receptor 4, activates monocytes in pre-eclamptic patients Pubmed: 24661950
European journal of pharmacology Suramin inhibits hepatic tissue damage in hepatocellular carcinoma through deactivation of heparanase enzyme Pubmed: 24530413
European Journal of Pharmacology Evaluation of antiglypican-3 therapy as a promising target for amelioration of hepatic tissue damage in hepatocellular carcinoma Pubmed:25449037
Shock Impairment of the Endothelial Glycocalyx in Cardiogenic Shock and its Prognostic Relevance Pubmed:25692257
Biomarkers in Medicine Endothelial glycocalyx layer shedding following lung resection pubmed:27643669
Apmis Circulating syndecans during critical illness. pubmed:28256016
Biomedicine & Pharmacotherapy Cytotoxic and partial hepatoprotective activity of sodium ascorbate against hepatocellular carcinoma through inhibition of sulfatase-2 and Pubmed:29669302
Drug Delivery Glioma targeting peptide modified apoferritin nanocage Pubmed:29726297
Anaesthesia Postoperative microcirculatory perfusion and endothelial glycocalyx shedding following cardiac surgery with cardiopulmonary bypass Pubmed: 30687934
Animals Diet Supplementation with a Bioactive Pomace Extract from Olea europaea Partially Mitigates Negative Effects on Gut Health Arising from a Short-Term Fasting Period …
LIFE SCIENCES Heparin prevents in vitro glycocalyx shedding induced by plasma from COVID-19 patients 33781826
Genet Mol Biol A novel mutation in ext2 caused hereditary multiple exostoses through reducing the synthesis of heparan sulfate 34042151
Poultry Science Response of broiler chickens fed diets supplemented with a bioactive olive pomace extract from Olea europaea to an experimental coccidial vaccine?¡­ 33518110
J Gerontol A Biol Sci Med Sci The effect of pre-operative methylprednisolone on postoperative delirium in elderly patients undergoing gastrointestinal surgery: a randomized, double-blind, placebo … 34423832
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPA565Hu01 Recombinant Heparan Sulfate Proteoglycan (HSPG) Positive Control; Immunogen; SDS-PAGE; WB.
PAA565Hu01 Polyclonal Antibody to Heparan Sulfate Proteoglycan (HSPG) WB; IHC; ICC; IP.
LAA565Hu71 Biotin-Linked Polyclonal Antibody to Heparan Sulfate Proteoglycan (HSPG) WB; IHC; ICC.
LAA565Hu81 FITC-Linked Polyclonal Antibody to Heparan Sulfate Proteoglycan (HSPG) WB; IHC; ICC; IF.
MAA565Hu22 Monoclonal Antibody to Heparan Sulfate Proteoglycan (HSPG) WB; IHC; ICC; IP.
SEA565Hu ELISA Kit for Heparan Sulfate Proteoglycan (HSPG) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA565Hu Multiplex Assay Kit for Heparan Sulfate Proteoglycan (HSPG) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
KSA565Hu01 ELISA Kit DIY Materials for Heparan Sulfate Proteoglycan (HSPG) Main materials for "Do It(ELISA Kit) Yourself"