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Recombinant Heparanase (HPSE)

HPA; HPR1; HPSE1; HSE1; Endo-glucoronidase;

  • Product No.RPA711Ra01
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationLysosome membrane; Peripheral membrane protein. Secreted. Nucle
  • Predicted Molecular Mass20.9kDa
  • Accurate Molecular Mass20.87kDa(Analysis of differences refer to the manual)
  • Residues & TagsArg40~Pro188 (Accession # Q71RP1) with
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point8.7
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 192  US$ 480  US$ 960  US$ 2880  US$ 7200 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in PBS or others.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Plos one PG545, a Heparan Sulfate Mimetic, Reduces Heparanase Expression In Vivo, Blocks Spontaneous Metastases and Enhances Overall Survival in the 4T1 Breast Carcinoma Model Plosone: Source
Journal of Medical Science Assessment of heparanase and heparin-binding growth and angiogenesis factors in the uterine cavity ? uid in women with impaired reproduction Nowinylekarskie:Source
Int J Clin Exp Pathol Unfractionated heparin attenuates intestinal injury in mouse model of sepsis by inhibiting heparanase PubMed: 26191183
Tumour Biology PI-88 inhibits postoperative recurrence of hepatocellular carcinoma via disrupting the surge of heparanase after liver resection PubMed: 26415733
Journal of Medical Science Assessment of heparanase and heparin-binding growth and angiogenesis factors in the uterine cavity fluid in women with impaired reproduction article:84
Renal Failure Plasma heparanase is associated with blood glucose levels but not urinary microalbumin excretion in type 2 diabetic nephropathy at the early stage pubmed:28994624
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
RPA711Ra01 Recombinant Heparanase (HPSE) Positive Control; Immunogen; SDS-PAGE; WB.
PAA711Ra01 Polyclonal Antibody to Heparanase (HPSE) WB; IHC; ICC; IP.
LAA711Ra71 Biotin-Linked Polyclonal Antibody to Heparanase (HPSE) WB; IHC; ICC.
MAA711Ra21 Monoclonal Antibody to Heparanase (HPSE) WB; IHC; ICC; IP.
MAA711Ra24 Monoclonal Antibody to Heparanase (HPSE) WB
MAA711Ra22 Monoclonal Antibody to Heparanase (HPSE) WB; IHC; ICC; IP.
MAA711Ra23 Monoclonal Antibody to Heparanase (HPSE) WB; IHC; ICC; IP.
SEA711Ra ELISA Kit for Heparanase (HPSE) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA711Ra Multiplex Assay Kit for Heparanase (HPSE) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.