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Recombinant Chemokine C-X-C-Motif Receptor 4 (CXCR4)

CD184; Fusin; NPYR; HSY3RR; LAP3; LCR1; LESTR; NPY3R; NPYRL; WHIM; Leukocyte-derived seven transmembrane domain receptor; Lipopolysaccharide-associated protein 3

  • Product No.RPA940Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane, Lysosome
  • Predicted Molecular Mass13.6kDa
  • Accurate Molecular Mass16kDa(Analysis of differences refer to the manual)
  • Residues & TagsAsp262~Ser352 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point8.6
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 174  US$ 436  US$ 872  US$ 2616  US$ 6540 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
International Journal of Cancer Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model Wiley: source
Plos one Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma PubMed: PMC3589458
Atherosclerosis The non-alcoholic fraction of beer increases stromal cell derived factor 1 and the number of circulating endothelial progenitor cells in high cardiovascular risk subjects: A randomized clinical trial Pubmed:24530788
Pharmacol Rep.? Comparison of chemokines (CCL-5 and SDF-1), chemokine receptors (CCR-5 and CXCR-4) and IL-6 levels in patients with different severities of depression Pubmed:25150002
Pharmacological Reports Serum concentrations of chemokines (CCL-5 and CXCL-12), chemokine receptors (CCR-5 and CXCR-4), and IL-6 in patients with posttraumatic stress disorder and avoidant personality disorder PubMed: 26481549
Pharmacological Reports A study of chemokines, chemokine receptors and interleukin-6 in patients with panic disorder, personality disorders and their co-morbidity Pubmed:27208878
BMC Cancer.  Enhancement of the CXCL12/CXCR4 axis due to acquisition of gemcitabine resistance in pancreatic cancer: effect of CXCR4 antagonists pmc:PMC4866076
Frontiers in Bioengineering and Biotechnology Matrix Metalloproteinase-2 Impairs Homing of Intracoronary Delivered Mesenchymal Stem Cells in a Porcine Reperfused Myocardial Infarction: Comparison … Pubmed:29670878
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPA940Hu01 Recombinant Chemokine C-X-C-Motif Receptor 4 (CXCR4) Positive Control; Immunogen; SDS-PAGE; WB.
CPA940Hu21 OVA Conjugated Chemokine C-X-C-Motif Receptor 4 (CXCR4) Immunogen; SDS-PAGE; WB.
PAA940Hu08 Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4) WB; IHC; ICC; IP.
PAA940Hu01 Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4) WB; IHC; ICC; IP.
FAA940Hu01 Anti-Chemokine C-X-C-Motif Receptor 4 (CXCR4) Polyclonal Antibody Flow cytometry.
FAA940Hu41 PE-Linked Anti-Chemokine C-X-C-Motif Receptor 4 (CXCR4) Polyclonal Antibody Flow cytometry.
FAA940Hu51 APC-Linked Anti-Chemokine C-X-C-Motif Receptor 4 (CXCR4) Polyclonal Antibody Flow cytometry.
FAA940Hu81 FITC-Linked Anti-Chemokine C-X-C-Motif Receptor 4 (CXCR4) Polyclonal Antibody Flow cytometry.
MAA940Hu22 Monoclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4) WB; IHC; ICC; IP.
RAA940Hu21 Recombinant Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4) WB; IF; ICC; IHC; IP; FCM.
SEA940Hu ELISA Kit for Chemokine C-X-C-Motif Receptor 4 (CXCR4) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA940Hu Multiplex Assay Kit for Chemokine C-X-C-Motif Receptor 4 (CXCR4) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.