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Recombinant Farnesoid X Receptor (FXR)

NR1H4; BAR; FXR; HRR1; RIP14; Nuclear Receptor Subfamily 1,Group H,Member 4; Bile acid receptor; Farnesol receptor HRR-1; Retinoid X receptor-interacting protein 14

  • Product No.RPC042Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationNucleus
  • Predicted Molecular Mass45.9kDa
  • Accurate Molecular Mass53kDa(Analysis of differences refer to the manual)
  • Residues & TagsLeu211~Gln486 with Two N-terminal Tags, His-tag and SUMO-tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point5.9
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 176  US$ 440  US$ 880  US$ 2640  US$ 6600 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
The Journal of Nutritional Biochemistry Raspberry pomace alters cecal microbial activity and reduces secondary bile acids in rats fed a high-fat diet. pubmed:28437712
Chinese Journal of Natural Medicines Hypolipidemic effect of SIPI-7623, a derivative of an extract from oriental wormwood, through farnesoid X receptor antagonism Pubmed: 30197122
Cytotechnology d-Allulose enhances uptake of HDL-cholesterol into rat's primary hepatocyte via SR-B1 Pubmed: 32086695
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPC042Hu01 Recombinant Farnesoid X Receptor (FXR) Positive Control; Immunogen; SDS-PAGE; WB.
PAC042Hu01 Polyclonal Antibody to Farnesoid X Receptor (FXR) WB; IHC; ICC; IP.
MAC042Hu22 Monoclonal Antibody to Farnesoid X Receptor (FXR) WB; IHC; ICC; IP.
SEC042Hu ELISA Kit for Farnesoid X Receptor (FXR) Enzyme-linked immunosorbent assay for Antigen Detection.
LMC042Hu Multiplex Assay Kit for Farnesoid X Receptor (FXR) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.