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Recombinant Growth Differentiation Factor 11 (GDF11)

BMP11; Bone morphogenetic protein 11

  • Product No.RPC113Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass31.9kDa
  • Accurate Molecular Mass33kDa(Analysis of differences refer to the manual)
  • Residues & TagsThr138~Asn386 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point9.1
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 184  US$ 460  US$ 920  US$ 2760  US$ 6900 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Oncotarget Splenocytes derived from young WT mice prevent AD progression in APPswe/PSENldE9 transgenic mice PubMed: 26317549
Endocrinology TGFβ Superfamily Members Mediate Androgen Deprivation Therapy-Induced Obese Frailty in Male Mice pubmed:27611336
International Journal of Clinical and Experimental Pathology GDF11 is increased in patients with myelodysplastic syndrome files:ijcep0024948.pdf
European Review for Medical and Pharmacological Sciences GDF11 does not improve the palmitate induced insulin resistance in C2C12. pubmed:28485800
CyberLeninka РОЛЬ ДИФФЕРЕНЦИРОВОЧНОГО ФАКТОРА РОСТА 11 (GDF11) В РЕГУЛЯЦИИ ЛИПИДНОГО ОБМЕНА И КАРДИОГЕМОДИНАМИЧЕСКИХ ФУНКЦИЙ … Cyberleninka:Source
Hematology GDF11 is increased in patients with aplastic anemia Pubmed: 30727851
J Cell Mol Me GDF11 prevents the formation of thoracic aortic dissection in mice: Promotion of contractile transition of aortic SMCs 33764670
Arch Gynecol Obstet The relationship between transforming growth factor β superfamily members (GDF11 and BMP4) and lumbar spine bone mineral density in postmenopausal Chinese … 34417839
Oxidative Medicine and Cellular Longevity Low-Intensity Exercise Routine for a Long Period of Time Prevents Osteosarcopenic Obesity in Sedentary Old Female Rats, by Decreasing Inflammation and … 34336096
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPC113Hu02 Recombinant Growth Differentiation Factor 11 (GDF11) Positive Control; Immunogen; SDS-PAGE; WB.
RPC113Hu01 Recombinant Growth Differentiation Factor 11 (GDF11) Positive Control; Immunogen; SDS-PAGE; WB.
PAC113Hu02 Polyclonal Antibody to Growth Differentiation Factor 11 (GDF11) WB; IHC; ICC; IP.
PAC113Hu01 Polyclonal Antibody to Growth Differentiation Factor 11 (GDF11) WB; IHC; ICC; IP.
MAC113Hu21 Monoclonal Antibody to Growth Differentiation Factor 11 (GDF11) WB
SEC113Hu ELISA Kit for Growth Differentiation Factor 11 (GDF11) Enzyme-linked immunosorbent assay for Antigen Detection.
SCC113Hu CLIA Kit for Growth Differentiation Factor 11 (GDF11) Chemiluminescent immunoassay for Antigen Detection.
LMC113Hu Multiplex Assay Kit for Growth Differentiation Factor 11 (GDF11) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.