CD25 is the α chain of IL-2R and a characteristic marker molecule on the surface of regulatory T (Treg) cells. Treg cells have immunosuppressive effects by inhibiting Th cells, CD8+T cell proliferation and activation, as well as NK cell-mediated killing activity. On the one hand, it can induce autoimmune tolerance, so as to maintain the stable state of the body and avoid the occurrence of autoimmune diseases; On the other hand, it can inhibit the formation and maintenance of tumor immune mechanism. Therefore, CD25 detection is of great significance in the prevention and treatment of autoimmune diseases and clinical tumors.2021-10-21

Pulmonary fibrosis (PF) is a major category of terminal changes of lung diseases characterized by proliferation of fibroblasts, accumulation of a large amount of extracellular matrix, accompanied by inflammatory damage and destruction of tissue structure, namely, structural abnormalities caused by abnormal repair of normal alveolar tissue after damage. The cause of most PF is unknown and is called idiopathic interstitial pneumonia. In idiopathic interstitial pneumonia, the most common disease type with PF lesions as the main manifestation is idiopathic PF, which is an interstitial lung disease that can lead to progressive loss of lung function.New progress in the research on the pathog......2021-10-19

CD8 refers to a molecule expressed on the surface of T lymphocytes. T lymphocytes expressing this molecule are called CD8+ T lymphocytes, which are cytotoxic T lymphocytes that can kill kill the human cells infected by the virus and tumor cells,block the replication and spread of viruses and the spread of tumors. Under normal circumstances, CD8 lymphocytes account for about 35% of all T lymphocytes. The increase of CD8+ T lymphocytes should consider that the human body is suffering from viral infection or the appearance of tumors, so CD8 detection is helpful for the diagnosis of certain infectious diseases and immune diseases.2021-10-13

The dangers of obesityThe persistent imbalance between energyintake and energy consumption results inobesity, which causes acommon disorder called metabolic syndrome, with various comorbidities. These include type 2 diabetes, hypertension, nonalcoholic steatohepatitis(NASH), cardiovascular diseases and cancer, which may lead to death. Worldwide, 1.9 billion adults are overweight and 600 million are obese, and 51% of the global population is predicted to be obese by 2030. Thus, obesity is a major global health problem with increasingly alarming incidence.New targets for obesity treatmentDespite efforts to find safe, effective obesity treatments, current options are limited, mainly due t......2021-09-29

2021-09-28

CD3 is the best marker for detecting mature T cells in peripheral blood. Therefore, the determination of CD3 positive T cells is of great significance to the evaluation of immunodeficiency, such as T cell deficiency, leukemia, lymphoma and so on. In addition, the CD3 monoclonal antibody is fully utilized in immunosuppressive therapy during organ transplantation, bone marrow transplantation, and immunomodulatory therapy for the purpose of removing T cells for severe autoimmune diseases.2021-09-27