8-Hydroxydeoxyguanosine (8-OHdG)


8OHdG; 7,8-Dihydro-8-Oxo-2'-Deoxyguanosine; 7,8-Dihydro-8-Oxodeoxyguanosine; 8-Hydroxy-2'-Deoxyguanosine; 8-Oxo-DG

8-Hydroxydeoxyguanosine (8-OHdG)

8-oxo-7,8-dihydro-2 deoxyguanosine(8-OHdG), is probably the most important product of "oxidative stress” in DNA. Its concentration in DNA is, in fact. a quantitative analysis of the degree of DNA damage that an organism has undergone. Due to the importance of 8-OHdG of nucleic acidg in mutagenesis, carcinogenesis and aging, numerous chemical and biological investigations have been made on this subject in the past time. Kuchino and co-workers have found that 8-OHdG residue in DNA is misreading during the process of DNA replication. Recently, some reports have been presented on high 8-OHdG levels in patients suffering from various diseases such as chronic hepatitis, Fanconi s anemia, diabetes mellitus and Helicobacter pylori infections. As a result, 8-OHdG is a useful marker for the study of DNA damage arising from reactive oxygen species and is of great significance for cancer research.

Organism species: Pan-species (General)

Proteins n/a Complete Antigen of 8-Hydroxydeoxyguanosine (8-OHdG) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to 8-Hydroxydeoxyguanosine (8-OHdG) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to 8-Hydroxydeoxyguanosine (8-OHdG) Polyclonal Antibody Customized Service Offer
Assay Kits CEA660Ge ELISA Kit for 8-Hydroxydeoxyguanosine (8-OHdG) Enzyme-linked immunosorbent assay for Antigen Detection.
CCA660Ge CLIA Kit for 8-Hydroxydeoxyguanosine (8-OHdG) Chemiluminescent immunoassay for Antigen Detection.