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Cytokeratin 8 (CK8)

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K8; CARD2; KRT8; CYK8; K2C8; KO; Keratin 8; Keratin, type II cytoskeletal 8

Cytokeratin 8 (CK8)
CCC C025
HGNC 6446
MGI 96705
PubMed 15368451
RGD 2984
UniProt P05787
Wiki Keratin_8

Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells.

This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.

The human and mouse CK8 share about 82% identity in the N-terminal head domain, 95% identity in the alpha helical rod domain, and 67.5% identity in the C-terminal tail.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC025Hu01 Recombinant Cytokeratin 8 (CK8) Positive Control; Immunogen; SDS-PAGE; WB.
RPC025Hu02 Recombinant Cytokeratin 8 (CK8) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC025Hu01 Polyclonal Antibody to Cytokeratin 8 (CK8) WB; IHC; ICC/IF; FCM
MAC025Hu22 Monoclonal Antibody to Cytokeratin 8 (CK8) IHC; ICC/IF
LAC025Hu71 Biotin-Linked Polyclonal Antibody to Cytokeratin 8 (CK8) IHC
LAC025Hu81 FITC-Linked Polyclonal Antibody to Cytokeratin 8 (CK8) WB; IHC; ICC; IF.
MAC025Hu21 Monoclonal Antibody to Cytokeratin 8 (CK8) WB; IHC; ICC/IF
MAC025Hu23 Monoclonal Antibody to Cytokeratin 8 (CK8) WB; IHC
PAC025Hu02 Polyclonal Antibody to Cytokeratin 8 (CK8) WB
Assay Kits SEC025Hu ELISA Kit for Cytokeratin 8 (CK8) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytokeratin 8 (CK8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytokeratin 8 (CK8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytokeratin 8 (CK8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytokeratin 8 (CK8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytokeratin 8 (CK8) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC025Ra01 Recombinant Cytokeratin 8 (CK8) Positive Control; Immunogen; SDS-PAGE; WB.
RPC025Ra02 Recombinant Cytokeratin 8 (CK8) Positive Control; Immunogen; SDS-PAGE; WB.
RPC025Ra03 Recombinant Cytokeratin 8 (CK8) Positive Control; Immunogen; SDS-PAGE; WB.
RPC025Ra04 Recombinant Cytokeratin 8 (CK8) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC025Ra01 Polyclonal Antibody to Cytokeratin 8 (CK8) WB; IHC
PAC025Ra02 Polyclonal Antibody to Cytokeratin 8 (CK8) WB; IHC; ICC/IF
LAC025Ra71 Biotin-Linked Polyclonal Antibody to Cytokeratin 8 (CK8) WB
PAC025Ra03 Polyclonal Antibody to Cytokeratin 8 (CK8) WB
Assay Kits n/a CLIA Kit for Cytokeratin 8 (CK8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytokeratin 8 (CK8) ELISA Kit Customized Service Offer
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