Interleukin 29 (IL29)

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IFNL1; IFN-λ1; Interferon Lambda 1; Cytokine Zcyto21

Interleukin 29 (IL29)

Interleukin-29 (IL-29) is a protein of the helical cytokine family and is a type III interferon. It is also known as IFN lambda1 and is highly similar in amino acid sequence to the IL-28, the other type III interferon.

IL-29 is a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC029Hu01 Recombinant Interleukin 29 (IL29) Positive Control; Immunogen; SDS-PAGE; WB.
APC029Hu01 Active Interleukin 29 (IL29) Cell culture; Activity Assays.
EPC029Hu61 Eukaryotic Interleukin 29 (IL29) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC029Hu01 Polyclonal Antibody to Interleukin 29 (IL29) WB; IHC; ICC; IP.
MAC029Hu22 Monoclonal Antibody to Interleukin 29 (IL29) WB; IHC
MAC029Hu21 Monoclonal Antibody to Interleukin 29 (IL29) IHC
MAC029Hu23 Monoclonal Antibody to Interleukin 29 (IL29) IHC
MAC029Hu24 Monoclonal Antibody to Interleukin 29 (IL29) IHC
MAC029Hu25 Monoclonal Antibody to Interleukin 29 (IL29) IHC
MAC029Hu27 Monoclonal Antibody to Interleukin 29 (IL29) IHC
Assay Kits SEC029Hu ELISA Kit for Interleukin 29 (IL29) Enzyme-linked immunosorbent assay for Antigen Detection.
SCC029Hu CLIA Kit for Interleukin 29 (IL29) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC029Ra01 Recombinant Interleukin 29 (IL29) Positive Control; Immunogen; SDS-PAGE; WB.
EPC029Ra61 Eukaryotic Interleukin 29 (IL29) Positive Control; Immunogen; SDS-PAGE; WB.
APC029Ra61 Active Interleukin 29 (IL29) Cell culture; Activity Assays.
Antibodies n/a Monoclonal Antibody to Interleukin 29 (IL29) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Interleukin 29 (IL29) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Interleukin 29 (IL29) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 29 (IL29) ELISA Kit Customized Service Offer

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC029Po01 Recombinant Interleukin 29 (IL29) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Interleukin 29 (IL29) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Interleukin 29 (IL29) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Interleukin 29 (IL29) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 29 (IL29) ELISA Kit Customized Service Offer
  1. "IL-28, IL-29 and their class II cytokine receptor IL-28R." Nat. Immunol. 4:63-68(2003) [PubMed] [Europe PMC] [Abstract]
  2. "IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex."Nat. Immunol. 4:69-77(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Interferon-lambda: a new addition to an old family."J. Interferon Cytokine Res. 30:555-564(2010) [PubMed] [Europe PMC] [Abstract]
  6. "Interferon-lambda in the context of viral infections: production, response and therapeutic implications."J. Innate Immun. 6:563-574(2014) [PubMed] [Europe PMC] [Abstract]
  7. "Crystal structure of human interferon-lambda1 in complex with its high-affinity receptor interferon-lambdaR1."J. Mol. Biol. 404:650-664(2010) [PubMed] [Europe PMC] [Abstract]
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