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Valosin Containing Protein (VCP)

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IBMPFD; p97; TERA; Transitional Endoplasmic Reticulum ATPase; 15S Mg(2+)-ATPase p97 subunit

Valosin Containing Protein (VCP)
CCC C601
HGNC 12666
MGI 99919
PubMed 11483959
RGD 621595
UniProt P55072
Wiki VCP
VCP is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. VCP, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. VCP has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.
Clathrin is a structural protein found in coated pits and vesicles, organelles which are important in membrane trafficking functions such as endocytosis and Golgi sorting. A 100-kD protein, designated valosin-containing protein or VCP by early investigators, is a structural protein complexed with clathrin.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC601Hu01 Recombinant Valosin Containing Protein (VCP) Positive Control; Immunogen; SDS-PAGE; WB.
APC601Hu01 Active Valosin Containing Protein (VCP) Cell culture; Activity Assays.
Antibodies PAC601Hu01 Polyclonal Antibody to Valosin Containing Protein (VCP) WB,IHC
MAC601Hu21 Monoclonal Antibody to Valosin Containing Protein (VCP) WB
Assay Kits SEC601Hu ELISA Kit for Valosin Containing Protein (VCP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC601Mu01 Recombinant Valosin Containing Protein (VCP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Valosin Containing Protein (VCP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Valosin Containing Protein (VCP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Valosin Containing Protein (VCP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Valosin Containing Protein (VCP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC601Ra01 Recombinant Valosin Containing Protein (VCP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC601Ra01 Polyclonal Antibody to Valosin Containing Protein (VCP) WB; IHC; ICC; IP.
MAC601Ra21 Monoclonal Antibody to Valosin Containing Protein (VCP) WB; IHC; ICC; IP.
Assay Kits SEC601Ra ELISA Kit for Valosin Containing Protein (VCP) Enzyme-linked immunosorbent assay for Antigen Detection.
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  6. , Submitted (NOV-2005) to UniProtKB
  7. "Valosin-containing protein, VCP, is a ubiquitous clathrin-binding protein."Nature 365:459-462(1993) [PubMed] [Europe PMC] [Abstract]