Progestagen Associated Endometrial Protein (PAEP)

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GD; GdA; GdF; GdS; PAEG; PEP; PP14; Glycodelin; Placental Protein 14; Alpha Uterine Protein; Pregnancy-Associated Endometrial Alpha-2-Globulin; Progesterone-associated

Progestagen Associated Endometrial Protein (PAEP)
Glycodelin is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9.
The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC709Hu01 Recombinant Progestagen Associated Endometrial Protein (PAEP) Positive Control; Immunogen; SDS-PAGE; WB.
EPC709Hu61 Eukaryotic Progestagen Associated Endometrial Protein (PAEP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC709Hu01 Polyclonal Antibody to Progestagen Associated Endometrial Protein (PAEP) WB; IHC; ICC; IP.
MAC709Hu22 Monoclonal Antibody to Progestagen Associated Endometrial Protein (PAEP) WB; IHC; ICC; IP.
MAC709Hu21 Monoclonal Antibody to Progestagen Associated Endometrial Protein (PAEP) WB
MAC709Hu23 Monoclonal Antibody to Progestagen Associated Endometrial Protein (PAEP) WB
Assay Kits SEC709Hu ELISA Kit for Progestagen Associated Endometrial Protein (PAEP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Progestagen Associated Endometrial Protein (PAEP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Progestagen Associated Endometrial Protein (PAEP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Progestagen Associated Endometrial Protein (PAEP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Progestagen Associated Endometrial Protein (PAEP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Progestagen Associated Endometrial Protein (PAEP) ELISA Kit Customized Service Offer
  1. "Complete amino acid sequence of human placental protein 14: a progesterone-regulated uterine protein homologous to beta-lactoglobulins."Proc. Natl. Acad. Sci. U.S.A. 85:8845-8849(1988) [PubMed] [Europe PMC] [Abstract]
  2. "Human placental protein 14 gene: sequence and characterization of a short duplication."DNA Cell Biol. 9:401-413(1990) [PubMed] [Europe PMC] [Abstract]
  3. "Multiple forms of mRNA encoding human pregnancy-associated endometrial alpha 2-globulin, a beta-lactoglobulin homologue."Proc. Natl. Acad. Sci. U.S.A. 88:2456-2460(1991) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  5. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Pregnancy-associated endometrial alpha 2-globulin, the major secretory protein of the luteal phase and first trimester pregnancy endometrium, is not glycosylated prolactin but related to beta-lactoglobulins."J. Clin. Endocrinol. Metab. 65:1067-1071(1987) [PubMed] [Europe PMC] [Abstract]
  8. "Amino acid sequence homology between human placental protein 14 and beta-lactoglobulins from various species."Endocrinology 120:2620-2622(1987) [PubMed] [Europe PMC] [Abstract]
  9. "Purification and characterization of an immunomodulatory endometrial protein, glycodelin."J. Biol. Chem. 276:17101-17105(2001) [PubMed] [Europe PMC] [Abstract]
  10. "Structural analysis of the oligosaccharides derived from glycodelin, a human glycoprotein with potent immunosuppressive and contraceptive activities."J. Biol. Chem. 270:24116-24126(1995) [PubMed] [Europe PMC] [Abstract]
  11. "Gender-specific glycosylation of human glycodelin affects its contraceptive activity."J. Biol. Chem. 271:32159-32167(1996) [PubMed] [Europe PMC] [Abstract]
  12. "Glycodelin from seminal plasma is a differentially glycosylated form of contraceptive glycodelin-A."Mol. Hum. Reprod. 2:759-765(1996) [PubMed] [Europe PMC] [Abstract]