Acetyl Coenzyme A Acyltransferase 2 (ACAA2)

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DSAEC; T1; Mitochondrial 3-Oxoacyl-Coenzyme A Thiolase; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase

Acetyl Coenzyme A Acyltransferase 2 (ACAA2)
Mammalian tissues have 5 known types of thiolase: ACAT2, which is involved in cholesterol biosynthesis, peroxisomal ACAA1, which is involved in beta-oxidation, mitochondrial ACAT1, which appears to function in ketone body metabolism, mitochondrial ACAA2, which catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral, and mitochondrial trifunctional protein, which also catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. The deduced 397-amino acid ACAA2 protein contains a putative 16-amino acid N-terminal mitochondrial targeting signal. Human and rat ACAA2 share 86.6% amino acid sequence identity. Northern blot analysis found a 1.6-kb ACAA2 transcript in human liver, fibroblasts, and intercostal muscle; ACAA2 expression was barely detectable in spleen and kidney.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD659Hu01 Recombinant Acetyl Coenzyme A Acyltransferase 2 (ACAA2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD659Hu01 Polyclonal Antibody to Acetyl Coenzyme A Acyltransferase 2 (ACAA2) WB; IHC; ICC; IP; FCM
Assay Kits n/a CLIA Kit for Acetyl Coenzyme A Acyltransferase 2 (ACAA2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acetyl Coenzyme A Acyltransferase 2 (ACAA2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD659Mu01 Recombinant Acetyl Coenzyme A Acyltransferase 2 (ACAA2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD659Mu01 Polyclonal Antibody to Acetyl Coenzyme A Acyltransferase 2 (ACAA2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Acetyl Coenzyme A Acyltransferase 2 (ACAA2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acetyl Coenzyme A Acyltransferase 2 (ACAA2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Acetyl Coenzyme A Acyltransferase 2 (ACAA2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Acetyl Coenzyme A Acyltransferase 2 (ACAA2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Acetyl Coenzyme A Acyltransferase 2 (ACAA2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Acetyl Coenzyme A Acyltransferase 2 (ACAA2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acetyl Coenzyme A Acyltransferase 2 (ACAA2) ELISA Kit Customized Service Offer
  1. "Cloning and sequence analysis of a full length cDNA encoding human mitochondrial 3-oxoacyl-CoA thiolase."Biochim. Biophys. Acta 1216:304-306(1993) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes."Biochem. J. 383:237-248(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Acetyl-Coenzyme A acyltransferase 2 attenuates the apoptotic effects of BNIP3 in two human cell lines."Biochim. Biophys. Acta 1780:873-880(2008) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]