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Dehydrogenase/Reductase SDR Family, Member 7 (DHRS7)

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SDR34C1; retDSR4; Retinal Short-Chain Dehydrogenase/Reductase 4; Short Chain Dehydrogenase/Reductase Family 34C,Member 1

Dehydrogenase/Reductase SDR Family, Member 7 (DHRS7)
CCC J149
HGNC 21524
MGI 1913625
PubMed 20872794
RGD 1308036
UniProt Q9Y394
Wiki DHRS7
Short-chain dehydrogenases/reductases (SDRs), such as DHRS7, catalyze the oxidation/reduction of a wide range of substrates, including retinoids and steroids.
By searching EST databases for SDRs, followed by 3-prime and 5-prime RACE and nested PCR of a human retina cDNA library, Haeseleer and Palczewski (2000) cloned DHRS7, which they called RETSDR4. The deduced 289-amino acid protein has a calculated molecular mass of 32.3 kD. It has all the characteristics of SDRs, including a cofactor-binding Rossman-fold domain and highly conserved motifs in the nucleotide-binding site and active site. Northern blot analysis detected DHRS7 expression in all tissues examined.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Dehydrogenase/Reductase SDR Family, Member 7 (DHRS7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Dehydrogenase/Reductase SDR Family, Member 7 (DHRS7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Dehydrogenase/Reductase SDR Family, Member 7 (DHRS7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Dehydrogenase/Reductase SDR Family, Member 7 (DHRS7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Dehydrogenase/Reductase SDR Family, Member 7 (DHRS7) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Dehydrogenase/Reductase SDR Family, Member 7 (DHRS7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Dehydrogenase/Reductase SDR Family, Member 7 (DHRS7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Dehydrogenase/Reductase SDR Family, Member 7 (DHRS7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Dehydrogenase/Reductase SDR Family, Member 7 (DHRS7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Dehydrogenase/Reductase SDR Family, Member 7 (DHRS7) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Dehydrogenase/Reductase SDR Family, Member 7 (DHRS7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Dehydrogenase/Reductase SDR Family, Member 7 (DHRS7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Dehydrogenase/Reductase SDR Family, Member 7 (DHRS7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Dehydrogenase/Reductase SDR Family, Member 7 (DHRS7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Dehydrogenase/Reductase SDR Family, Member 7 (DHRS7) ELISA Kit Customized Service Offer
  1. "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics."Genome Res. 10:703-713(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Short-chain dehydrogenases/reductases in retina."Methods Enzymol. 316:372-383(2000) [PubMed] [Europe PMC] [Abstract]
  3. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]