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Ubiquitin Cross Reactive Protein (UCRP)

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G1P2; IFI15; ISG15; Interferon Alpha-Inducible Protein clone IFI-15K; Interferon Induced Protein 15; Interferon-induced 17 kDa protein

Ubiquitin Cross Reactive Protein (UCRP)
CCC L630
HGNC 4053
MGI 1855694
PubMed 15670748
RGD 1310312
UniProt P05161
Wiki ISG15

ISG15 shares several common properties with other ubiquitin-like molecules (UBLs), but its activity is tightly regulated by specific signaling pathways that have a role in innate immunity. ISG15 was identified as an interferon stimulated gene (ISG) since its expression is induced in response to type I interferons or lipopolysaccharide treatment. Upon interferon treatment, ISG15 can be detected in both free and conjugated forms, and is secreted from monocytes and lymphocytes where it can function as a cytokine. In the cell, ISG15 co-localizes with intermediate filaments and ISGylation may modulate the JAK-STAT pathway or certain aspects of neurological disease. It is also known as UCRP (ubiquitin cross-reactive protein) since it contains 2 tandem ubiquitin homology domains and is cross-reactive with ubiquitin antibodies.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPL630Hu01 Recombinant Ubiquitin Cross Reactive Protein (UCRP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAL630Hu01 Polyclonal Antibody to Ubiquitin Cross Reactive Protein (UCRP) WB; IHC
MAL630Hu21 Monoclonal Antibody to Ubiquitin Cross Reactive Protein (UCRP) WB
MAL630Hu22 Monoclonal Antibody to Ubiquitin Cross Reactive Protein (UCRP) WB
MAL630Hu23 Monoclonal Antibody to Ubiquitin Cross Reactive Protein (UCRP) WB
MAL630Hu24 Monoclonal Antibody to Ubiquitin Cross Reactive Protein (UCRP) WB
MAL630Hu25 Monoclonal Antibody to Ubiquitin Cross Reactive Protein (UCRP) WB
MAL630Hu26 Monoclonal Antibody to Ubiquitin Cross Reactive Protein (UCRP) WB
MAL630Hu27 Monoclonal Antibody to Ubiquitin Cross Reactive Protein (UCRP) WB
MAL630Hu28 Monoclonal Antibody to Ubiquitin Cross Reactive Protein (UCRP) WB
Assay Kits SEL630Hu ELISA Kit for Ubiquitin Cross Reactive Protein (UCRP) Enzyme-linked immunosorbent assay for Antigen Detection.
SCL630Hu CLIA Kit for Ubiquitin Cross Reactive Protein (UCRP) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPL630Mu01 Recombinant Ubiquitin Cross Reactive Protein (UCRP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAL630Mu01 Polyclonal Antibody to Ubiquitin Cross Reactive Protein (UCRP) WB
Assay Kits n/a CLIA Kit for Ubiquitin Cross Reactive Protein (UCRP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ubiquitin Cross Reactive Protein (UCRP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ubiquitin Cross Reactive Protein (UCRP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ubiquitin Cross Reactive Protein (UCRP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ubiquitin Cross Reactive Protein (UCRP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ubiquitin Cross Reactive Protein (UCRP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ubiquitin Cross Reactive Protein (UCRP) ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPL630Bo01 Recombinant Ubiquitin Cross Reactive Protein (UCRP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Ubiquitin Cross Reactive Protein (UCRP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ubiquitin Cross Reactive Protein (UCRP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ubiquitin Cross Reactive Protein (UCRP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ubiquitin Cross Reactive Protein (UCRP) ELISA Kit Customized Service Offer
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