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Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 4 (LILRA4)

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CD85g; ILT7; CD85 antigen-like family member G; Immunoglobulin-like transcript 7

Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 4 (LILRA4)
CCC L667
HGNC 15503
PubMed 19388928
UniProt P59901
Wiki LILRA4
LILRA4 encodes an immunoglobulin-like cell surface protein preferentially expressed in plasmacytoid dendritic cells (PDCs). This gene is highly expressed in PDCs, and is found to be rapidly down-regulated by interleukin 3 (IL3). This gene is one of the 19 highly related genes that form a leukocyte receptor gene cluster (LRC) at chromosomal region 19q13.4.
By subtractive hybridization, Rissoan et al. (2002) identified LILRA4, which they designated ILT7, as 1 of several transcripts expressed at high levels in plasmacytoid dendritic cells (PDCs). In addition to PDCs, RT-PCR detected expression in monocytes and activated B lymphocytes, but not in monocyte-derived dendritic cells. Weak expression was observed in thymus cDNA.LILRA4 expression was rapidly downregulated in PDCs by interleukin-3 (IL3).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 4 (LILRA4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 4 (LILRA4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 4 (LILRA4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 4 (LILRA4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 4 (LILRA4) ELISA Kit Customized Service Offer
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  5. "Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction."J. Exp. Med. 206:1603-1614(2009) [PubMed] [Europe PMC] [Abstract]