≡

USP6 N-Terminal Like Protein (USP6NL)

[Edit]

RNTRE; TRE2NL; Related to the N-terminus of tre

USP6 N-Terminal Like Protein (USP6NL)
CCC L872
HGNC 16858
MGI 2138893
PubMed 8700515
RGD 1311786
UniProt Q92738
Wiki USP6NL
RNTRE is a 97- to 100-kD protein that stably associates in vivo and in vitro with EPS8 via the SH3 domain of the latter. In vitro, RNTRE displayed remarkable preference for binding to the SH3 domain of EPS8, compared with 8 other SH3s. A C-terminal truncated mutant of RNTRE was able to confer proliferative advantage and reduced serum requirement to NIH 3T3 fibroblasts, suggesting a role for RNTRE in cell proliferation.
Because the 828-amino acid protein encoded by this cDNA shows homology to the N-terminal region of the TRE oncogene, the authors designated it RNTRE, for 'related to the N terminus of TRE.' RNTRE was shown to be ubiquitously expressed.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPL872Hu01 Recombinant USP6 N-Terminal Like Protein (USP6NL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAL872Hu01 Polyclonal Antibody to USP6 N-Terminal Like Protein (USP6NL) WB; IHC; ICC; IP.
MAL872Hu21 Monoclonal Antibody to USP6 N-Terminal Like Protein (USP6NL) WB; IHC; ICC; IP.
Assay Kits SEL872Hu ELISA Kit for USP6 N-Terminal Like Protein (USP6NL) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant USP6 N-Terminal Like Protein (USP6NL) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to USP6 N-Terminal Like Protein (USP6NL) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to USP6 N-Terminal Like Protein (USP6NL) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for USP6 N-Terminal Like Protein (USP6NL) CLIA Kit Customized Service Offer
n/a ELISA Kit for USP6 N-Terminal Like Protein (USP6NL) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant USP6 N-Terminal Like Protein (USP6NL) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to USP6 N-Terminal Like Protein (USP6NL) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to USP6 N-Terminal Like Protein (USP6NL) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for USP6 N-Terminal Like Protein (USP6NL) CLIA Kit Customized Service Offer
n/a ELISA Kit for USP6 N-Terminal Like Protein (USP6NL) ELISA Kit Customized Service Offer
  1. "RN-tre identifies a family of tre-related proteins displaying a novel potential protein binding domain."Oncogene 12:2563-2571(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity."Genes Cells 14:41-52(2009) [PubMed] [Europe PMC] [Abstract]
  3. "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1."DNA Res. 1:27-35(1994) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Normalization and subtraction: two approaches to facilitate gene discovery."Genome Res. 6:791-806(1996) [PubMed] [Europe PMC] [Abstract]
  8. "The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5."Nature 408:374-377(2000) [PubMed] [Europe PMC] [Abstract]
  9. "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry."Anal. Chem. 76:2763-2772(2004) [PubMed] [Europe PMC] [Abstract]
  10. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  11. "Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways."J. Cell Biol. 177:1133-1143(2007) [PubMed] [Europe PMC] [Abstract]
  12. "Analysis of GTPase-activating proteins: Rab1 and Rab43 are key Rabs required to maintain a functional Golgi complex in human cells."J. Cell Sci. 120:2997-3010(2007) [PubMed] [Europe PMC] [Abstract]
  13. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  14. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  15. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  16. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  17. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  18. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  19. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]