Twinfilin 1 (TWF1)

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A6; PTK9; Actin-Binding Protein,Homolog 1; Protein Tyrosine Kinase 9

Twinfilin 1 (TWF1)
TWF1 encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1.
The deduced 350-amino acid protein has a calculated molecular mass of 40.3 kD. TWF1 has an N-myristoylation site and several sites for threonine, serine, and tyrosine phosphorylation, but it lacks a conserved protein kinase catalytic domain. Northern blot analysis detected a 3.4-kb transcript that was highly expressed in colon, testis, uterus, ovary, prostate, and lung. Lower expression was detected in brain, bladder, and heart, and no expression was detected in liver.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM410Hu01 Recombinant Twinfilin 1 (TWF1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAM410Hu01 Polyclonal Antibody to Twinfilin 1 (TWF1) WB; FCM
LAM410Hu71 Biotin-Linked Polyclonal Antibody to Twinfilin 1 (TWF1) WB; IHC; ICC.
LAM410Hu81 FITC-Linked Polyclonal Antibody to Twinfilin 1 (TWF1) WB; IHC; ICC; IF.
MAM410Hu21 Monoclonal Antibody to Twinfilin 1 (TWF1) WB; IHC; ICC; IP.
Assay Kits SEM410Hu ELISA Kit for Twinfilin 1 (TWF1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Twinfilin 1 (TWF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Twinfilin 1 (TWF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Twinfilin 1 (TWF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Twinfilin 1 (TWF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Twinfilin 1 (TWF1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Twinfilin 1 (TWF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Twinfilin 1 (TWF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Twinfilin 1 (TWF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Twinfilin 1 (TWF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Twinfilin 1 (TWF1) ELISA Kit Customized Service Offer
  1. "Prokaryotic expression cloning of a novel human tyrosine kinase."Mol. Cell. Biol. 14:982-988(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]