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Interleukin 1 Theta (IL1q)

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IL1F10; IL38; FKSG75; IL-1HY2; IL-1F10; FIL1-Theta; Interleukin-38; Interleukin-1 Receptor Antagonist FKSG75; Interleukin 1 Family, Member 10

Interleukin 1 Theta (IL1q)
CCC Q458
HGNC 15552
MGI 2652548
PubMed 11747621
RGD 1305635
UniProt Q8WWZ1
Wiki IL1F10
IL1F10 is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses.
IL-1F10 shares characteristics of the IL-1Ra family, including key amino acid consensus sequences and a similar genomic structure. By multitissue first-strand cDNA PCR analysis, IL-1F10 mRNA is expressed in heart, placenta, fetal liver, spleen, thymus, and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-1F10 in the inflammatory response.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ458Hu01 Recombinant Interleukin 1 Theta (IL1q) Positive Control; Immunogen; SDS-PAGE; WB.
APQ458Hu01 Active Interleukin 1 Theta (IL1q) Cell culture; Activity Assays.
Antibodies PAQ458Hu01 Polyclonal Antibody to Interleukin 1 Theta (IL1q) WB; IHC; ICC; IP.
Assay Kits SEQ458Hu ELISA Kit for Interleukin 1 Theta (IL1q) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Interleukin 1 Theta (IL1q) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Interleukin 1 Theta (IL1q) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Interleukin 1 Theta (IL1q) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Interleukin 1 Theta (IL1q) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 1 Theta (IL1q) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Interleukin 1 Theta (IL1q) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Interleukin 1 Theta (IL1q) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Interleukin 1 Theta (IL1q) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Interleukin 1 Theta (IL1q) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 1 Theta (IL1q) ELISA Kit Customized Service Offer
  1. "Identification of a novel human cytokine gene in the interleukin gene cluster on chromosome 2q12-14."J. Interferon Cytokine Res. 21:899-904(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning and characterization of IL1HY2, a novel interleukin-1 family member."J. Biol. Chem. 276:20597-20602(2001) [PubMed] [Europe PMC] [Abstract]
  3. "A sequence-based map of the nine genes of the human interleukin-1 cluster."Genomics 79:718-725(2002) [PubMed] [Europe PMC] [Abstract]
  4. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  5. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist."Proc. Natl. Acad. Sci. U.S.A. 109:3001-3005(2012) [PubMed] [Europe PMC] [Abstract]
  8. "Genomic organization of the interleukin-1 locus."Genomics 79:726-733(2002) [PubMed] [Europe PMC] [Abstract]