Interleukin 3 (IL3)

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MCGF; MULTI-CSF; MCSF; M-CSF; Multiple; Multilineage-Colony-Stimulating Factor; Hematopoietic Growth Factor; P-Cell Stimulating Factor; Mast-Cell Growth Factor

Interleukin 3 (IL3)

Interleukin-3 (IL-3) is an interleukin, a type of biological signal (cytokine) that can improve the body's natural response to disease as part of the immune system. It acts by binding to the Interleukin-3 receptor.

IL-3 stimulates the differentiation of multipotent hematopoietic stem cells into myeloid progenitor cells as well as stimulates proliferation of all cells in the myeloid lineage (erythrocytes, thrombocytes, granulocytes, monocytes, and dendritic cells). It is secreted by activated T cells to support growth and differentiation of T cells from the bone marrow in an immune response. Interleukin-3 is a hematopoietic colony-stimulating factor that is capable of supporting the proliferation of a broad range of hematopoietic cell types. Interleukin-3 also has neurotrophic activity .

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA076Hu01 Recombinant Interleukin 3 (IL3) Positive Control; Immunogen; SDS-PAGE; WB.
APA076Hu01 Active Interleukin 3 (IL3) Cell culture; Activity Assays.
Antibodies PAA076Hu01 Polyclonal Antibody to Interleukin 3 (IL3) WB; IHC; ICC; IP.
MAA076Hu22 Monoclonal Antibody to Interleukin 3 (IL3) WB; IHC; ICC; IP.
Assay Kits SEA076Hu ELISA Kit for Interleukin 3 (IL3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA076Mu01 Recombinant Interleukin 3 (IL3) Positive Control; Immunogen; SDS-PAGE; WB.
RPA076Mu02 Recombinant Interleukin 3 (IL3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA076Mu01 Polyclonal Antibody to Interleukin 3 (IL3) WB; IHC; ICC; IP.
PAA076Mu02 Polyclonal Antibody to Interleukin 3 (IL3) WB; IHC; ICC; IP.
Assay Kits SEA076Mu ELISA Kit for Interleukin 3 (IL3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA076Ra01 Recombinant Interleukin 3 (IL3) Positive Control; Immunogen; SDS-PAGE; WB.
RPA076Ra02 Recombinant Interleukin 3 (IL3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA076Ra01 Polyclonal Antibody to Interleukin 3 (IL3) WB; IHC; ICC; IP.
MAA076Ra21 Monoclonal Antibody to Interleukin 3 (IL3) WB; IHC; ICC; IP.
PAA076Ra02 Polyclonal Antibody to Interleukin 3 (IL3) WB; IHC; ICC; IP.
Assay Kits SEA076Ra ELISA Kit for Interleukin 3 (IL3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA076Ca01 Recombinant Interleukin 3 (IL3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA076Ca01 Polyclonal Antibody to Interleukin 3 (IL3) WB; IHC; ICC; IP.
MAA076Ca21 Monoclonal Antibody to Interleukin 3 (IL3) WB; IHC; ICC; IP.
Assay Kits SEA076Ca ELISA Kit for Interleukin 3 (IL3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Capra hircus; Caprine (Goat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA076Cp01 Recombinant Interleukin 3 (IL3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA076Cp01 Polyclonal Antibody to Interleukin 3 (IL3) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Interleukin 3 (IL3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 3 (IL3) ELISA Kit Customized Service Offer

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA076Ga01 Recombinant Interleukin 3 (IL3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA076Ga01 Polyclonal Antibody to Interleukin 3 (IL3) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Interleukin 3 (IL3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 3 (IL3) ELISA Kit Customized Service Offer
  1. "Characterization of a human multilineage-colony-stimulating factor cDNA clone identified by a conserved noncoding sequence in mouse interleukin-3."Gene 55:115-124(1987) [PubMed] [Europe PMC] [Abstract]
  2. "Isolation and characterization of an expressible cDNA encoding human IL-3. Induction of IL-3 mRNA in human T cell clones."J. Immunol. 140:2288-2295(1988) [PubMed] [Europe PMC] [Abstract]
  3. "Human IL-3 (multi-CSF): identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3."Cell 47:3-10(1986) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Molecular characterization of colony-stimulating factors and their receptors: human interleukin-3."Ann. N. Y. Acad. Sci. 554:167-176(1989) [PubMed] [Europe PMC] [Abstract]
  7. "Three-dimensional solution structure and backbone dynamics of a variant of human interleukin-3."J. Mol. Biol. 259:524-541(1996) [PubMed] [Europe PMC] [Abstract]