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Chemokine (C-X-C Motif) Ligand 2 (CXCL2)

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GROb; SCYB2; MIP2; GRO2; MIP2a; MGSAb; CINC2a; HSF; Macrophage inflammatory protein 2-alpha; Hematopoietic synergistic factor; Growth Regulated Oncogene Beta

Chemokine (C-X-C Motif) Ligand 2 (CXCL2)
CCC B603
HGNC 4603
MGI 1340094
PubMed 17944017
RGD 70069
UniProt P19875
Wiki CXCL2

Growth-regulated oncogene (GRO)beta, which belongs to the CXC chemokine family, is a potent chemoattractant for neutrophils.Chemokine (C-X-C motif) ligand 2 (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2). CXCL2 is 90% identical in amino acid sequence as a related chemokine, CXCL1.

This chemokine is secreted by monocytes and macrophages and is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. The gene for CXCL2 is located on human chromosome 4 in a cluster of other CXC chemokines.CXCL2 mobilizes cells by interacting with a cell surface chemokine receptor called CXCR2.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB603Hu01 Recombinant Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Positive Control; Immunogen; SDS-PAGE; WB.
RPB603Hu02 Recombinant Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Positive Control; Immunogen; SDS-PAGE; WB.
RPB603Hu03 Recombinant Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Positive Control; Immunogen; SDS-PAGE; WB.
APB603Hu01 Active Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Cell culture; Activity Assays.
Antibodies PAB603Hu01 Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 2 (CXCL2) WB; IHC; ICC; IP.
MAB603Hu22 Monoclonal Antibody to Chemokine (C-X-C Motif) Ligand 2 (CXCL2) WB; IHC; ICC; IP.
PAB603Hu02 Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 2 (CXCL2) WB,IHC
LAB603Hu71 Biotin-Linked Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 2 (CXCL2) WB; IHC; ICC.
PAB603Hu03 Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 2 (CXCL2) WB; IHC; ICC; IP.
Assay Kits SEB603Hu ELISA Kit for Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Enzyme-linked immunosorbent assay for Antigen Detection.
SCB603Hu CLIA Kit for Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB603Mu01 Recombinant Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Positive Control; Immunogen; SDS-PAGE; WB.
EPB603Mu51 Eukaryotic Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Positive Control; Immunogen; SDS-PAGE; WB.
RPB603Mu02 Recombinant Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB603Mu01 Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 2 (CXCL2) WB; IHC; ICC; IP.
PAB603Mu07 Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 2 (CXCL2) WB; IHC; ICC; IP.
PAB603Mu02 Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 2 (CXCL2) WB; IHC; ICC; IP.
PAB603Mu51 Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 2 (CXCL2) WB; IHC; ICC; IP.
Assay Kits SEB603Mu ELISA Kit for Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB603Ra01 Recombinant Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Positive Control; Immunogen; SDS-PAGE; WB.
APB603Ra01 Active Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Cell culture; Activity Assays.
Antibodies PAB603Ra01 Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 2 (CXCL2) WB; IHC; ICC; IP.
MAB603Ra21 Monoclonal Antibody to Chemokine (C-X-C Motif) Ligand 2 (CXCL2) WB; IHC; ICC; IP.
Assay Kits SEB603Ra ELISA Kit for Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Equus caballus; Equine (Horse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB603Eq01 Recombinant Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB603Eq01 Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 2 (CXCL2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Chemokine (C-X-C Motif) Ligand 2 (CXCL2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chemokine (C-X-C Motif) Ligand 2 (CXCL2) ELISA Kit Customized Service Offer
  1. "Cloning and characterization of cDNAs for murine macrophage inflammatory protein 2 and its human homologues."J. Exp. Med. 172:911-919(1990) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning and sequencing of a new gro transcript from activated human monocytes: expression in leukocytes and wound tissue."Mol. Cell. Biol. 10:5596-5599(1990) [PubMed] [Europe PMC] [Abstract]
  3. "Identification of three related human GRO genes encoding cytokine functions."Proc. Natl. Acad. Sci. U.S.A. 87:7732-7736(1990) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Monocyte adherence results in selective induction of novel genes sharing homology with mediators of inflammation and tissue repair."J. Immunol. 144:4434-4441(1990) [PubMed] [Europe PMC] [Abstract]
  6. "Identification of unique truncated KC/GRO beta chemokines with potent hematopoietic and anti-infective activities."J. Immunol. 164:3774-3782(2000) [PubMed] [Europe PMC] [Abstract]
  7. "Nuclear magnetic resonance solution structure of truncated human GRObeta [5-73] and its structural comparison with CXC chemokine family members GROalpha and IL-8."J. Mol. Biol. 294:1065-1072(1999) [PubMed] [Europe PMC] [Abstract]