Eukaryotic Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF)

ARMET; ARP; Arginine Rich Mutated In Early Stage Tumors; Arginine-rich protein

  • Product No.EPC300Hu61
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceEukaryotic expression
  • Host293F cell
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass19.8kDa
  • Accurate Molecular Mass21kDa(Analysis of differences refer to the manual)
  • Residues & TagsLeu25~Leu182 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 97%
  • Isoelectric Point8.4
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 168  US$ 420  US$ 840  US$ 2520  US$ 6300 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
PLoS One. Molecular Effects of Doxycycline Treatment on Pterygium as Revealed by Massive Transcriptome Sequencing PubMed: PMC3378547
Endocr J. Circulating mesencephalic astrocyte-derived neurotrophic factor is increased in newly diagnosed prediabetic and diabetic patients, and is associated with insulin resistance. pubmed:28216543
Journal of Steroid Biochemistry and Molecular Biology Depressive-like effect of prenatal exposure to DDT involves global DNA hypomethylation and impairment of GPER1/ESR1 protein levels but not ESR2 and AHR/ARNT signaling pubmed:28263910
Endocrine Journal Circulating mesencephalic astrocyte-derived neurotrophic factor is increased in newly diagnosed prediabetic and diabetic patients, and is associated with insulin resistance 10.1507:endocrj.EJ16-0472
Nature Metabolism MANF regulates metabolic and immune homeostasis in ageing and protects against liver damage
J Exp Med Feeding-induced hepatokine, Manf, ameliorates diet-induced obesity by promoting adipose browning via p38 MAPK pathway 33856409
J Inflamm Res The Potential Protective Effect of Mesencephalic Astrocyte-Derived Neurotrophic Factor on Post-Operative Delirium via Inhibiting Inflammation and Microglia … 34234505
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
APC300Hu61 Active Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) Cell culture; Activity Assays.
EPC300Hu61 Eukaryotic Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) Positive Control; Immunogen; SDS-PAGE; WB.
APC300Hu01 Active Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) Cell culture; Activity Assays.
RPC300Hu01 Recombinant Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) Positive Control; Immunogen; SDS-PAGE; WB.
PAC300Hu01 Polyclonal Antibody to Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) WB; IHC; ICC; IP.
MAC300Hu25 Monoclonal Antibody to Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) WB
MAC300Hu21 Monoclonal Antibody to Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) WB; IHC; ICC; IP.
MAC300Hu23 Monoclonal Antibody to Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) WB; IHC; ICC; IP.
MAC300Hu24 Monoclonal Antibody to Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) WB; IHC; ICC; IP.
MAC300Hu27 Monoclonal Antibody to Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) WB; IHC; ICC; IP.
MAC300Hu22 Monoclonal Antibody to Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) WB,IHC
MEC300Hu Mini Samples ELISA Kit for Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) Enzyme-linked immunosorbent assay for Antigen Detection.
SEC300Hu ELISA Kit for Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) Enzyme-linked immunosorbent assay for Antigen Detection.
LMC300Hu Multiplex Assay Kit for Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
KSC300Hu01 ELISA Kit DIY Materials for Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) Main materials for "Do It(ELISA Kit) Yourself"