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Recombinant Hexosaminidase A Alpha (HEXa)

TSD; Hex-A; Tay Sachs Disease; GM2 Gangliosidosis; Beta-Hexosaminidase Subunit Alpha; Beta-N-Acetylhexosaminidase Subunit Alpha; N-Acetyl-Beta-Glucosaminidase Alpha

  • Product No.RPA195Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationLysosome
  • Predicted Molecular Mass28.4kDa
  • Accurate Molecular Mass28kDa(Analysis of differences refer to the manual)
  • Residues & TagsHis318~Thr529 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point5.7
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 172  US$ 430  US$ 860  US$ 2580  US$ 6450 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Neural Regen Res Functionality of a bicistronic construction containing HEXA and HEXB genes encoding ¦Â-hexosaminidase A for cell-mediated therapy of GM2 gangliosidoses 34100447
life Serum Cytokine Profile, Beta-Hexosaminidase A Enzymatic Activity and GM2 Ganglioside Levels in the Plasma of a Tay-Sachs Disease Patient after Cord Blood Cell … 34685379
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPA195Hu01 Recombinant Hexosaminidase A Alpha (HEXa) Positive Control; Immunogen; SDS-PAGE; WB.
PAA195Hu01 Polyclonal Antibody to Hexosaminidase A Alpha (HEXa) WB; IHC; ICC; IP.
MAA195Hu22 Monoclonal Antibody to Hexosaminidase A Alpha (HEXa) WB; IHC; ICC; IP.
SEA195Hu ELISA Kit for Hexosaminidase A Alpha (HEXa) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA195Hu Multiplex Assay Kit for Hexosaminidase A Alpha (HEXa) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.