Recombinant Parathyroid Hormone Related Protein (PTHrP)
PTHLH; HHM; PTHR; PLP; Osteostatin; Parathyroid Hormone Like Hormone
- Product No.RPA819Ca01
- Organism SpeciesCanis familiaris; Canine (Dog) Same name, Different species.
- SourceProkaryotic expression
- Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
- Subcellular LocationSecreted
- Predicted Molecular Mass22.8kDa
- Accurate Molecular Mass26kDa(Analysis of differences refer to the manual)
- Residues & TagsAla37~His177 with N-terminal His Tag
- Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- Traits Freeze-dried powder
- Purity> 95%
- Isoelectric Point9.3
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
- DownloadInstruction Manual
- UOM 10µg50µg 200µg 1mg 5mg
For more details, please contact local distributors! 380 US$ 380
For more details, please contact local distributors! US$ 760
For more details, please contact local distributors! US$ 2280
For more details, please contact local distributors! US$ 5700
For more details, please contact local distributors!
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
- Endotoxin Removal Kit
- BCA Protein Quantification Kit
- Protein Labeling Customized Service
- Molecular Mass Marker for Protein
- Recombinant Protein Customized Service
- Monoclonal Antibody Customized Service
- Polyclonal Antibody Customized Service
- Protein Activity Test Experiment Service
- Immunoprecipitation (IP) Experiment Service
- Endotoxin Removal Kit II
- Real Time PCR Experimental Service
- Spike RBD Protein (S-RBD)
- Protein G
- Protein A
|Clinical and Experimental Metastasis||Characterization of a new renal cell carcinoma bone metastasis mouse model PubMed: 20443133|
|Stem Cells and Development||Temporal activation of β-catenin signaling in the chondrogenic process of mesenchymal stem cells affects the phenotype of the cartilage generated. PubMed: 22133004|
|International journal of biological sciences||PTHrP Expression in Human MDA-MB-231 Breast Cancer Cells Is Critical for Tumor Growth and Survival and Osteoblast Inhibition PubMed: PMC3753447|
|Investigational New Drugs||Tetrahydrofurofuran-type lignans inhibit breast cancer-mediated bone destruction by blocking the vicious cycle between cancer cells, osteoblasts and osteoclasts Pubmed: 23673814|
|Toxicology and Applied Pharmacology||Betulinic acid, a bioactive pentacyclic triterpenoid, inhibits skeletal-related events induced by breast cancer bone metastases and treatment Pubmed:24463094|
|Arch Gynecol Obstet.||Calcitonin gene-and parathyroid hormone-related peptides in normotensive and preeclamptic pregnancies: a nested case–control study Pubmed:24943060|
|PLoS One||15-Deoxy-Δ12, 14-Prostaglandin J2 Inhibits Osteolytic Breast Cancer Bone Metastasis and Estrogen Deficiency-Induced Bone Loss PubMed: 25859665|
|Endocrinology||A role for the calcitonin receptor to limit bone loss during lactation in female mice by inhibiting osteocytic osteolysis PubMed: 26135836|
|Tumour Biol||Osteopontin expression in co-cultures of human squamous cell carcinoma-derived cells and osteoblastic cells and its effects on the neoplastic cell phenotype and osteoclastic activation. Pubmed:27312487|
|35||Hedgehog signaling in bone regulates whole-body energy metabolism through a bone–adipose endocrine relay mediated by PTHrP and adiponectin pubmed:27740628|
|Bone||Lactation induces increases in the RANK/RANKL/OPG system in maxillary bone Pubmed:29382610|
|International Journal of Molecular Sciences||A Diet Rich in Fish Oil and Leucine Ameliorates Hypercalcemia in Tumour-Induced Cachectic Mice Pubmed: 31600911|
|Journal of Orthopaedic Surgery and Research||Identification of a potential gene target for osteoarthritis based on bioinformatics analyses Pubmed: 32571421|
|International Immunopharmacology||Parathyroid hormone related protein (PTHrP)-mediated hypercalcemia in malignancy associated with anti-PD-1 immune checkpoint inhibitor treatment and related …|
|Паратиреоидный гормон-родственный протеин как предиктор развития мочекаменной болезни|
|Cell Death Dis||Extracellular vesicles-released parathyroid hormone-related protein from Lewis lung carcinoma induces lipolysis and adipose tissue browning in cancer ¡ 33510128|
|Sci Rep||Effects of whole-body vibration training in a cachectic C26 mouse model 34732809|
|Acta Physiologica||The acute adaptation of renal phosphate transporters in the murine kidney to oral phosphate intake requires multiple signals Pubmed:35334154|
|Catalog No.||Related products for research use of Canis familiaris; Canine (Dog) Organism species||Applications (RESEARCH USE ONLY!)|
|RPA819Ca01||Recombinant Parathyroid Hormone Related Protein (PTHrP)||Positive Control; Immunogen; SDS-PAGE; WB.|
|PAA819Ca01||Polyclonal Antibody to Parathyroid Hormone Related Protein (PTHrP)||WB; IHC; ICC; IP.|
|LAA819Ca71||Biotin-Linked Polyclonal Antibody to Parathyroid Hormone Related Protein (PTHrP)||WB; IHC; ICC.|
|MAA819Ca21||Monoclonal Antibody to Parathyroid Hormone Related Protein (PTHrP)||WB; IHC; ICC; IP.|