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Recombinant Ferrochelatase (FECH)

EPP; FCE; Protoheme Ferrolyase; Protoporphyria; Heme synthase; Protoheme ferro-lyase

  • Product No.RPC488Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMitochondrion
  • Predicted Molecular Mass45.9kDa
  • Accurate Molecular Mass43kDa(Analysis of differences refer to the manual)
  • Residues & TagsGly55~Leu423 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point8.6
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 164  US$ 410  US$ 820  US$ 2460  US$ 6150 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Free Radical Biology and Medicine Flavonoid 4, 4′-dimethoxychalcone induced ferroptosis in cancer cells by synergistically activating Keap1/Nrf2/HMOX1 pathway and inhibiting FECH Pubmed:35697292
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPC488Hu01 Recombinant Ferrochelatase (FECH) Positive Control; Immunogen; SDS-PAGE; WB.
PAC488Hu01 Polyclonal Antibody to Ferrochelatase (FECH) WB; IHC; ICC; IP.
MAC488Hu22 Monoclonal Antibody to Ferrochelatase (FECH) WB; IHC; ICC; IP.
SEC488Hu ELISA Kit for Ferrochelatase (FECH) Enzyme-linked immunosorbent assay for Antigen Detection.
LMC488Hu Multiplex Assay Kit for Ferrochelatase (FECH) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
PGC488Hu01 Primer Pair for Ferrochelatase (FECH) PCR