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Recombinant High Temperature Requirement Factor A1 (HTRA1)

HtrA; L56; ORF480; PRSS11; HtrA Serine Peptidase 1; Protease,Serine,11; IGFBP5-Protease; High-temperature requirement A serine peptidase 1

  • Product No.RPL604Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted, Cytoplasm
  • Predicted Molecular Mass47.2kDa
  • Accurate Molecular Mass47kDa(Analysis of differences refer to the manual)
  • Residues & TagsGly204~Leu364 with N-terminal His and GST Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point6.6
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 220  US$ 550  US$ 1100  US$ 3300  US$ 8250 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Placenta Alterations of maternal plasma HTRA1 level in preeclampsia complicated by IUGR PubMed: 23083999
Placenta Upregulation of HtrA4 in the placentas of patients with severe pre-eclampsia PubMed: 22964307
Exp Gerontol Association of frailty with the serine protease HtrA1 in older adults Pubmed:27058767
International Journal of Clinical and Experimental Pathology HtrA1 up-regulates expression of MMPs via Erk1/2/Rock-dependent pathways files:ijcep0069706.pdf
Pregnancy Hypertension Association between first trimester plasma htra1 level and subsequent preeclampsia: a possible early marker?
American journal of translational research HtrA1 upregulates the expression of ADAMTS-5 in HNPCs via the ERK/NF-κB/JNK signaling pathway Pubmed: 31497227
J Matern Fetal Neonatal Med First trimester HtrA1 maternal plasma level and spontaneous preterm birth Pubmed: 32102578
BMC Geriatr Cross-sectional associations among P3NP, HtrA, Hsp70, Apelin and sarcopenia in Taiwanese population 33743591
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPL604Hu01 Recombinant High Temperature Requirement Factor A1 (HTRA1) Positive Control; Immunogen; SDS-PAGE; WB.
PAL604Hu01 Polyclonal Antibody to High Temperature Requirement Factor A1 (HTRA1) WB; IHC; ICC; IP.
LAL604Hu71 Biotin-Linked Polyclonal Antibody to High Temperature Requirement Factor A1 (HTRA1) WB; IHC; ICC.
SEL604Hu ELISA Kit for High Temperature Requirement Factor A1 (HTRA1) Enzyme-linked immunosorbent assay for Antigen Detection.
SCL604Hu CLIA Kit for High Temperature Requirement Factor A1 (HTRA1) Chemiluminescent immunoassay for Antigen Detection.
LML604Hu Multiplex Assay Kit for High Temperature Requirement Factor A1 (HTRA1) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.