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Follicle Stimulating Hormone Beta (FSHb)

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FSH-B; Follitropin Subunit Beta

Follicle Stimulating Hormone Beta (FSHb)
CCC D017
HGNC 3964
MGI 95582
PubMed 3139991
RGD 2630
UniProt P01225
Wiki FSHB

Follitropin subunit beta is a protein encoded by the FSHB gene.The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein.Defects in FSHB are a cause of isolated follicle- stimulating hormone deficiency (IFSHD). Stimulates development of follicle and spermatogenesis in the reproductive organs.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins CPD017Hu21 OVA Conjugated Follicle Stimulating Hormone Beta (FSHb) Immunogen; SDS-PAGE; WB.
RPD017Hu01 Recombinant Follicle Stimulating Hormone Beta (FSHb) Positive Control; Immunogen; SDS-PAGE; WB.
EPD017Hu61 Eukaryotic Follicle Stimulating Hormone Beta (FSHb) Positive Control; Immunogen; SDS-PAGE; WB.
RPD017Hu02 Recombinant Follicle Stimulating Hormone Beta (FSHb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD017Hu08 Polyclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) WB; IHC; ICC; IP.
PAD017Hu01 Polyclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) WB; IHC; ICC; IP.
MAD017Mi21 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) WB; IHC
MAD017Mi22 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) WB; IHC
MAD017Hu21 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) WB
PAD017Hu02 Polyclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Follicle Stimulating Hormone Beta (FSHb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Follicle Stimulating Hormone Beta (FSHb) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins CPD017Mu21 OVA Conjugated Follicle Stimulating Hormone Beta (FSHb) Immunogen; SDS-PAGE; WB.
RPD017Mu01 Recombinant Follicle Stimulating Hormone Beta (FSHb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD017Mu08 Polyclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) WB; IHC; ICC; IP.
MAD017Mu21 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) IHC
PAD017Mu01 Polyclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) WB; IHC
MAD017Mu22 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) IHC
MAD017Mu23 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) IHC
MAD017Mu24 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) IHC
MAD017Mu25 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) IHC
Assay Kits SED017Mu ELISA Kit for Follicle Stimulating Hormone Beta (FSHb) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD017Ra01 Recombinant Follicle Stimulating Hormone Beta (FSHb) Positive Control; Immunogen; SDS-PAGE; WB.
CPD017Ra21 OVA Conjugated Follicle Stimulating Hormone Beta (FSHb) Immunogen; SDS-PAGE; WB.
Antibodies PAD017Ra01 Polyclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) WB; IHC
PAD017Ra08 Polyclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) WB; IHC; ICC; IP.
MAD017Ra21 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) WB; IHC
MAD017Ra22 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) IHC
MAD017Ra23 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) IHC
MAD017Ra24 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) IHC
MAD017Ra25 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) IHC
MAD017Ra27 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) IHC
MAD017Ra29 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) IHC
Assay Kits n/a CLIA Kit for Follicle Stimulating Hormone Beta (FSHb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Follicle Stimulating Hormone Beta (FSHb) ELISA Kit Customized Service Offer

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD017Po01 Recombinant Follicle Stimulating Hormone Beta (FSHb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD017Po01 Polyclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) WB; IHC
MAD017Mi21 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) WB; IHC
MAD017Mi22 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) WB; IHC
MAD017Mi23 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) IHC
MAD017Mi24 Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) IHC
Assay Kits n/a CLIA Kit for Follicle Stimulating Hormone Beta (FSHb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Follicle Stimulating Hormone Beta (FSHb) ELISA Kit Customized Service Offer

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD017Ga01 Recombinant Follicle Stimulating Hormone Beta (FSHb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Follicle Stimulating Hormone Beta (FSHb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Follicle Stimulating Hormone Beta (FSHb) ELISA Kit Customized Service Offer

Organism species: Danio rerio (Zebrafish)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD017Fi01 Recombinant Follicle Stimulating Hormone Beta (FSHb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD017Fi01 Polyclonal Antibody to Follicle Stimulating Hormone Beta (FSHb) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Follicle Stimulating Hormone Beta (FSHb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Follicle Stimulating Hormone Beta (FSHb) ELISA Kit Customized Service Offer
  1. "DNA sequence and regional assignment of the human follicle-stimulating hormone beta-subunit gene to the short arm of human chromosome 11."DNA 6:205-212(1987) [PubMed] [Europe PMC] [Abstract]
  2. "Expression of biologically active human follitropin in Chinese hamster ovary cells."J. Biol. Chem. 264:4769-4775(1989) [PubMed] [Europe PMC] [Abstract]
  3. "Human follicle-stimulating hormone beta-subunit gene encodes multiple messenger ribonucleic acids."Mol. Endocrinol. 2:806-815(1988) [PubMed] [Europe PMC] [Abstract]
  4. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "A reevaluation of the amino acid sequence of human follitropin beta-subunit."J. Protein Chem. 7:325-339(1988) [PubMed] [Europe PMC] [Abstract]
  7. "Amino acid sequence of the beta subunit of follicle-stimulating hormone from human pituitary glands."J. Biol. Chem. 251:993-1005(1976) [PubMed] [Europe PMC] [Abstract]
  8. "Human follicle stimulating hormone: first proposal for the amino acid sequence of the hormone-specific, beta subunit (hFSHb)."J. Clin. Endocrinol. Metab. 39:203-205(1974) [PubMed] [Europe PMC] [Abstract]
  9. "Studies on the disulfide bonds in human pituitary follicle-stimulating hormone."Biochim. Biophys. Acta 624:428-435(1980) [PubMed] [Europe PMC] [Abstract]
  10. "Assignment of the complete disulphide bridge pattern in the human recombinant follitropin beta-chain."Biol. Chem. 382:961-968(2001) [PubMed] [Europe PMC] [Abstract]
  11. "Three-dimensional structure of human follicle-stimulating hormone."Mol. Endocrinol. 15:378-389(2001) [PubMed] [Europe PMC] [Abstract]
  12. "Structure of human follicle-stimulating hormone in complex with its receptor."Nature 433:269-277(2005) [PubMed] [Europe PMC] [Abstract]
  13. "Primary amenorrhoea and infertility due to a mutation in the beta-subunit of follicle-stimulating hormone."Nat. Genet. 5:83-86(1993) [PubMed] [Europe PMC] [Abstract]
  14. "Delayed puberty and hypogonadism caused by mutations in the follicle-stimulating hormone beta-subunit gene."N. Engl. J. Med. 337:607-611(1997) [PubMed] [Europe PMC] [Abstract]
  15. "Isolated deficiency of follicle-stimulating hormone re-revisited."N. Engl. J. Med. 337:642-642(1997) [PubMed] [Europe PMC] [Abstract]
  16. "Characterization of single-nucleotide polymorphisms in coding regions of human genes."Nat. Genet. 22:231-238(1999) [PubMed] [Europe PMC] [Abstract]
  17. ErratumNat. Genet. 23:373-373(1999)
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