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Eukaryotic Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)

HB-EGF; DTR; DTS; DTSF; HEGFL; Diphtheria Toxin Receptor; Proheparin-binding EGF-like growth factor; Diphtheria toxin receptor

  • Product No.EPB479Hu61
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceEukaryotic expression
  • Host293F cell
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane, Secreted
  • Predicted Molecular Mass17.2kDa
  • Accurate Molecular Mass18kDa(Analysis of differences refer to the manual)
  • Residues & TagsVal21~Thr160 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point9.7
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 168  US$ 420  US$ 840  US$ 2520  US$ 6300 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Neuropathology Astrocyte ERK phosphorylation precedes K+-induced swelling but follows hypotonicity-induced swelling. PubMed: 21118399
Toxicological Sciences Cypermethrin Induces Astrocyte Apoptosis by the Disruption of the Autocrine/Paracrine Mode of Epidermal Growth Factor Receptor Signaling Pubmed: source
PAIN RESEARCH 軽度炎症性膀胱痛マウスモデルの構築とNGFの関与 Jstage:Source
European Journal of Pain A novel method for assessing bladder-related pain reveals the involvement of nerve growth factor in painassociated with cyclophosphamide-induced chronic cystitis in mice. Pubmed:25820250
Kinki daigaku 2 型糖尿病モデルラットにおける糖尿病性腎症の進行とHB-EGF の関連性 17844
laboratory investigation Heparin-binding epidermal growth factor contributes to COPD disease severity by modulating airway fibrosis and pulmonary epithelial–mesenchymal transition Pubmed:29581578
International Journal of Biological Sciences CD9 regulates keratinocyte migration by negatively modulating the sheddase activity of ADAM17
Redox Biology Tumoral NOX4 recruits M2 tumor-associated macrophages via ROS/PI3K signaling-dependent various cytokine production to promote NSCLC growth Pubmed: 30769285
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE Polarization of ADAM17‐driven EGFR signalling in electric field‐guided collective migration of epidermal sheets Pubmed: 33164313
象牙芽細胞の枯渇は象牙芽細胞分化と象牙質形成を誘導する
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
APB479Hu01 Active Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF) Cell culture; Activity Assays.
APB479Hu61 Active Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF) Cell culture; Activity Assays.
EPB479Hu61 Eukaryotic Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF) Positive Control; Immunogen; SDS-PAGE; WB.
RPB479Hu01 Recombinant Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF) Positive Control; Immunogen; SDS-PAGE; WB.
PAB479Hu01 Polyclonal Antibody to Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF) WB,IHC
LAB479Hu71 Biotin-Linked Polyclonal Antibody to Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF) WB; IHC; ICC.
MAB479Hu22 Monoclonal Antibody to Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF) WB; IHC; ICC; IP.
MAB479Hu21 Monoclonal Antibody to Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF) WB; IHC; ICC; IP.
MAB479Hu23 Monoclonal Antibody to Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF) WB; IHC; ICC; IP.
MAB479Hu24 Monoclonal Antibody to Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF) WB; IHC; ICC; IP.
SEB479Hu ELISA Kit for Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF) Enzyme-linked immunosorbent assay for Antigen Detection.
SCB479Hu CLIA Kit for Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF) Chemiluminescent immunoassay for Antigen Detection.
LMB479Hu Multiplex Assay Kit for Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.