Monoclonal Antibody to Procollagen I N-Terminal Propeptide (PINP)
P1NP; N-Propeptide Of Type I Procollagen; Procollagen I Amino Terminal Propeptide
- Product No.MAA957Hu21
- Organism SpeciesHomo sapiens (Human) Same name, Different species.
- SourceMonoclonal antibody preparation
- Potency (Clone Number)C6
- Ig Isotype IgG1 Kappa
- PurificationProtein A + Protein G affinity chromatography
- Immunogen RPA957Hu01-Recombinant Procollagen I N-Terminal Propeptide (PINP)
- Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
- Organism Species MoreMus musculus (Mouse), Rattus norvegicus (Rat)
- ApplicationsWB; IHC; ICC; IP;ELISA.
If the antibody is used in flow cytometry, please check FCM antibodies.
- DownloadInstruction Manual
- UOM 20µl100µl 200µl 1ml 10ml
For more details, please contact local distributors! US$ 385
For more details, please contact local distributors! US$ 550
For more details, please contact local distributors! US$ 1375
For more details, please contact local distributors! US$ 5500
For more details, please contact local distributors!
The antibody is a mouse monoclonal antibody raised against PINP. It has been selected for its ability to recognize PINP in immunohistochemical staining and western blotting.
Western blotting: 0.5-2µg/mL;1:500-2000
Optimal working dilutions must be determined by end user.
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
|Trials||Is there benefit in optimising heart failure treatment in over-80 year-old patients? (HF-80 study): study protocol for a randomized controlled trial. Trials: 1745-6215|
|Clinical Biochemistry||Measurement of aminoterminal propeptide of type I procollagen (PINP) in serum ScienceDirect: S0009912012001543|
|Therapeutic Apheresis and Dialysis||Low molecular weight iron dextran increases fibroblast growth factor-23 concentration, together with parathyroid hormone decrease in hemodialyzed patients PubMed: 22458393|
|International Journal of Clinical & Experimental Pathology||IL4 and IL-17A provide a Th2/Th17-polarized inflammatory milieu in favor of TGF-β1 to induce bronchial epithelial-mesenchymal transition (EMT) PubMed: PMC3726963|
|Osteoporosis International||PINP as a biological response marker during teriparatide treatment for osteoporosis Pubmed: 24599274|
|Clinical Cancer Research||Zoledronic acid has differential anti-tumour activity in the pre-and post-menopausal bone microenvironment in vivo Aacrjournals: Source|
|Endocrinology||Oxytocin Reverses Ovariectomy-Induced Osteopenia and Body Fat Gain Endocrine: Source|
|general endocrinology||Oxytocin reverse ovariectomy-induced Osteoper and body fat gain Pubmed:24506069|
|J Neurol Sci.||The effect of topiramate and lamotrigine on rat bone mass, structure and metabolism. Pubmed:24629477|
|Bone.||Neurofibromin inactivation impairs osteocyte development in Nf1Prx1 and Nf1Col1 mouse models Pubmed:24947449|
|Journal of Materials Science: Materials in Medicine||Phosphatidylethanolamine biomimetic coating increases mesenchymal stem cell osteoblastogenesis Pubmed:24980874|
|Springerplus.||Effects of de-escalated bisphosphonate therapy on bone turnover biomarkers in breast cancer patients with bone metastases Pubmed:25332877|
|Pharmacology||Effect of Mirtazapine on Rat Bone Tissue after Orchidectomy PubMed: 25871861|
|frontiers in endocrinology||Oxytocin reverses osteoporosis in a sex-dependent manner PubMed: 26042090|
|MERIT RESEARCH JOURNALS||Changes in Bone Metabolism Months after Laparoscopic Morbidly Obese Pre-menopausal Women Mms: Content|
|Heart Rhythm.||Prognostic value of collagen turnover biomarkers in cardiac resynchronization therapy: A subanalysis of the TRUST CRT randomized trial population Pubmed:26776557|
|BMJ Open Sport Exerc Med||Procollagen markers in microdialysate can predict patient outcome after Achilles tendon rupture content:2|
|Bibliothekssystem Universität Hamburg||Bilaterale Kommunikation zwischen Osteoblasten und Osteoklasten volltexte:2016|
|Inflammation Research||Fibrosis of extracellular matrix is related to the duration of the disease but is unrelated to the dynamics of collagen metabolism in dilated cardiomyopathy pubmed:27516211|
|Endocrine||Bone turnover response is linked to both acute and established metabolic changes in ultra-marathon runners pubmed:27422791|
|Heart & Vessels||Left ventricular reverse remodeling is not related to biopsy-detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR pubmed:28004175|
|journal of science and medicine in sport||The effect of calcium and vitamin D supplementation on bone health of male Jockeys. pubmed:27568072|
|Combined aerobic and resistance training improves bone health of female cancer survivors S2352187216300389|
|Cellular Physiology and Biochemistry||Renal Denervation Attenuates Multi-Organ Fibrosis and Improves Vascular Remodeling in Rats with Transverse Aortic Constriction Induced Cardiomyopathy pubmed:27889753|
|Epilepsy Research||The effect of lamotrigine and phenytoin on bone turnover and bone strength: A prospective study in Wistar rats pubmed:27838501|
|Sci Rep.||Sprint Interval Training Induces A Sexual Dimorphism but does not Improve Peak Bone Mass in Young and Healthy Mice. pubmed:28303909|
|Metabolism.||Low periostin levels in adult patients with Langerhans cell histiocytosis are independently associated with the disease activity. pubmed:28521873|
|Heart and vessels||Erratum to: Effects on bone metabolism markers and arterial stiffness by switching to rivaroxaban from warfarin in patients with atrial fibrillation pubmed:28314975|
|SCIENCE & TECHNOLOGY||A Study Protocol: Spinal Morphology, Physical Performance, Quality of Life and Biochemical Markers in Adults at Risk of Osteoporotic Fractures 59f7c85aaca272607e2d8d7a|
|Knee Surg Sports Traumatol Arthrosc||Achilles tendon rupture healing is enhanced by intermittent pneumatic compression upregulating collagen type I synthesis pubmed:28668970|
|Method for the treatment of cardiovascular fibrosis patents:US9594083|
|Clinical Cases in Mineral and Bone Metabolism||Periostin and sclerostin levels in juvenile Paget's disease pubmed:29263750|
|Journal of Clinical Research in Pediatric Endocrinology||Congenital Hypothyroidism and Bone Remodeling Cycle pubmed:27840329|
|Biomarkers Medicial||Relationship of biomarkers of extracellular matrix with myocardial function in Type 2 diabetes mellitus pubmed:28685602|
|Heart and Vessels||Left ventricular reverse remodeling is not related to biopsy‑detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR 10.1007/s00380-016-0930-y|
|BioMed Research International||Optimization of the Time Window of Interest in Ovariectomized Imprinting Control Region Mice for Antiosteoporosis Research pubmed:29119115|
|Cytokine||12-month patterns of serum markers of collagen synthesis, transforming growth factor and connective tissue growth factor are similar in new-onset and chronic dilated cardiomyopathy in patients both with and without cardiac fibrosis. pubmed:28460256|
|Advanced Healthcare Materials||Prognostic value of fibrosis-related markers in dilated cardiomyopathy: A link between osteopontin and cardiovascular events. pubmed:29120858|
|Bone.||The key role of proinflammatory cytokines, matrix proteins, RANKL/OPG and Wnt/β-catenin in bone healing of hip arthroplasty patients pubmed:29129760|
|Cell Death And Differentiation||TSC1 regulates osteoclast podosome organization and bone resorption through mTORC1 and Rac1/Cdc42 Pubmed:29358671|
|Nutrients||Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women—A Randomized Controlled Study Pubmed:29337906|
|Osteoporosis International||Two-year cortical and trabecular bone loss in CKD-5D: biochemical and clinical predictors Pubmed:28993865|
|Journal of Nutrition||Cholecalciferol Supplementation Promotes Bone Turnover in Chinese Adults with Vitamin D Deficiency Pubmed:29897564|
|European Journal of Pharmacology||The effect of levetiracetam on rat bone mineral density, bone structure and biochemical markers of bone metabolism Pubmed:29428468|
|Journal of Clinical Densitometry||Geometric and mechanical bone response to a multidisciplinary weight loss intervention in adolescents with obesity: The ADIBOX study Pubmed:30076009|
|Hernia||Circulating matrix metalloproteinases and procollagen propeptides in inguinal hernia Pubmed:29484522|
|Pharmacology||Effects of Amlodipine on Bone Metabolism in Orchidectomised Spontaneously Hypertensive Rats Pubmed:29898457|