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Synthetic Procollagen I N-Terminal Propeptide (PINP)
P1NP; N-Propeptide Of Type I Procollagen; Procollagen I Amino Terminal Propeptide
- Product No.SPA957Hu02
- Organism SpeciesHomo sapiens (Human) Same name, Different species.
- SourcePeptide synthesis
- Predicted Molecular Mass1633.8Da
- Buffer FormulationPBS, pH7.4.
- Traits Freeze-dried powder
- Purity> 95%
- Isoelectric Point4.3
-
Applications
Immunogen; Blocking Peptide.
If bio-activity of the protein is needed, please check active protein. - DownloadInstruction Manual
- UOM 10µg50µg 200µg 1mg 5mg
- FOB
US$ 132
For more details, please contact local distributors! US$ 330
For more details, please contact local distributors! US$ 660
For more details, please contact local distributors! US$ 1980
For more details, please contact local distributors! US$ 4950
For more details, please contact local distributors!
SEQUENCE
USAGE
Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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| Trials | Is there benefit in optimising heart failure treatment in over-80 year-old patients? (HF-80 study): study protocol for a randomized controlled trial. Trials: 1745-6215 |
| Clinical Biochemistry | Measurement of aminoterminal propeptide of type I procollagen (PINP) in serum ScienceDirect: S0009912012001543 |
| Therapeutic Apheresis and Dialysis | Low molecular weight iron dextran increases fibroblast growth factor-23 concentration, together with parathyroid hormone decrease in hemodialyzed patients PubMed: 22458393 |
| International Journal of Clinical & Experimental Pathology | IL4 and IL-17A provide a Th2/Th17-polarized inflammatory milieu in favor of TGF-β1 to induce bronchial epithelial-mesenchymal transition (EMT) PubMed: PMC3726963 |
| Osteoporosis International | PINP as a biological response marker during teriparatide treatment for osteoporosis Pubmed: 24599274 |
| Clinical Cancer Research | Zoledronic acid has differential anti-tumour activity in the pre-and post-menopausal bone microenvironment in vivo Aacrjournals: Source |
| Endocrinology | Oxytocin Reverses Ovariectomy-Induced Osteopenia and Body Fat Gain Endocrine: Source |
| general endocrinology | Oxytocin reverse ovariectomy-induced Osteoper and body fat gain Pubmed:24506069 |
| J Neurol Sci. | The effect of topiramate and lamotrigine on rat bone mass, structure and metabolism. Pubmed:24629477 |
| Bone. | Neurofibromin inactivation impairs osteocyte development in Nf1Prx1 and Nf1Col1 mouse models Pubmed:24947449 |
| Journal of Materials Science: Materials in Medicine | Phosphatidylethanolamine biomimetic coating increases mesenchymal stem cell osteoblastogenesis Pubmed:24980874 |
| Springerplus. | Effects of de-escalated bisphosphonate therapy on bone turnover biomarkers in breast cancer patients with bone metastases Pubmed:25332877 |
| Pharmacology | Effect of Mirtazapine on Rat Bone Tissue after Orchidectomy PubMed: 25871861 |
| frontiers in endocrinology | Oxytocin reverses osteoporosis in a sex-dependent manner PubMed: 26042090 |
| MERIT RESEARCH JOURNALS | Changes in Bone Metabolism Months after Laparoscopic Morbidly Obese Pre-menopausal Women Mms: Content |
| Heart Rhythm. | Prognostic value of collagen turnover biomarkers in cardiac resynchronization therapy: A subanalysis of the TRUST CRT randomized trial population Pubmed:26776557 |
| BMJ Open Sport Exerc Med | Procollagen markers in microdialysate can predict patient outcome after Achilles tendon rupture content:2 |
| Bibliothekssystem Universität Hamburg | Bilaterale Kommunikation zwischen Osteoblasten und Osteoklasten volltexte:2016 |
| Inflammation Research | Fibrosis of extracellular matrix is related to the duration of the disease but is unrelated to the dynamics of collagen metabolism in dilated cardiomyopathy pubmed:27516211 |
| Endocrine | Bone turnover response is linked to both acute and established metabolic changes in ultra-marathon runners pubmed:27422791 |
| Heart & Vessels | Left ventricular reverse remodeling is not related to biopsy-detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR pubmed:28004175 |
| journal of science and medicine in sport | The effect of calcium and vitamin D supplementation on bone health of male Jockeys. pubmed:27568072 |
| Combined aerobic and resistance training improves bone health of female cancer survivors S2352187216300389 | |
| Cellular Physiology and Biochemistry | Renal Denervation Attenuates Multi-Organ Fibrosis and Improves Vascular Remodeling in Rats with Transverse Aortic Constriction Induced Cardiomyopathy pubmed:27889753 |
| Epilepsy Research | The effect of lamotrigine and phenytoin on bone turnover and bone strength: A prospective study in Wistar rats pubmed:27838501 |
| Sci Rep. | Sprint Interval Training Induces A Sexual Dimorphism but does not Improve Peak Bone Mass in Young and Healthy Mice. pubmed:28303909 |
| Metabolism. | Low periostin levels in adult patients with Langerhans cell histiocytosis are independently associated with the disease activity. pubmed:28521873 |
| Heart and vessels | Erratum to: Effects on bone metabolism markers and arterial stiffness by switching to rivaroxaban from warfarin in patients with atrial fibrillation pubmed:28314975 |
| SCIENCE & TECHNOLOGY | A Study Protocol: Spinal Morphology, Physical Performance, Quality of Life and Biochemical Markers in Adults at Risk of Osteoporotic Fractures 59f7c85aaca272607e2d8d7a |
| Knee Surg Sports Traumatol Arthrosc | Achilles tendon rupture healing is enhanced by intermittent pneumatic compression upregulating collagen type I synthesis pubmed:28668970 |
| Method for the treatment of cardiovascular fibrosis patents:US9594083 | |
| Clinical Cases in Mineral and Bone Metabolism | Periostin and sclerostin levels in juvenile Paget's disease pubmed:29263750 |
| Journal of Clinical Research in Pediatric Endocrinology | Congenital Hypothyroidism and Bone Remodeling Cycle pubmed:27840329 |
| Biomarkers Medicial | Relationship of biomarkers of extracellular matrix with myocardial function in Type 2 diabetes mellitus pubmed:28685602 |
| Heart and Vessels | Left ventricular reverse remodeling is not related to biopsy‑detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR 10.1007/s00380-016-0930-y |
| BioMed Research International | Optimization of the Time Window of Interest in Ovariectomized Imprinting Control Region Mice for Antiosteoporosis Research pubmed:29119115 |
| Cytokine | 12-month patterns of serum markers of collagen synthesis, transforming growth factor and connective tissue growth factor are similar in new-onset and chronic dilated cardiomyopathy in patients both with and without cardiac fibrosis. pubmed:28460256 |
| Advanced Healthcare Materials | Prognostic value of fibrosis-related markers in dilated cardiomyopathy: A link between osteopontin and cardiovascular events. pubmed:29120858 |
| Bone. | The key role of proinflammatory cytokines, matrix proteins, RANKL/OPG and Wnt/β-catenin in bone healing of hip arthroplasty patients pubmed:29129760 |
| Cell Death And Differentiation | TSC1 regulates osteoclast podosome organization and bone resorption through mTORC1 and Rac1/Cdc42 Pubmed:29358671 |
| Nutrients | Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women—A Randomized Controlled Study Pubmed:29337906 |
| Osteoporosis International | Two-year cortical and trabecular bone loss in CKD-5D: biochemical and clinical predictors Pubmed:28993865 |
| Journal of Nutrition | Cholecalciferol Supplementation Promotes Bone Turnover in Chinese Adults with Vitamin D Deficiency Pubmed:29897564 |
| European Journal of Pharmacology | The effect of levetiracetam on rat bone mineral density, bone structure and biochemical markers of bone metabolism Pubmed:29428468 |
| Journal of Clinical Densitometry | Geometric and mechanical bone response to a multidisciplinary weight loss intervention in adolescents with obesity: The ADIBOX study Pubmed:30076009 |
| Hernia | Circulating matrix metalloproteinases and procollagen propeptides in inguinal hernia Pubmed:29484522 |
| Pharmacology | Effects of Amlodipine on Bone Metabolism in Orchidectomised Spontaneously Hypertensive Rats Pubmed:29898457 |