Active Interleukin 34 (IL34)
C16orf77
- Product No.APC007Mu01
- Organism SpeciesMus musculus (Mouse) Same name, Different species.
- Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
- Traits Freeze-dried powder
- Purity> 95%
- Isoelectric Point7.7
- ApplicationsCell culture; Activity Assays.
- DownloadInstruction Manual
- UOM 10µg50µg 200µg 1mg 5mg
- FOB
    
                                    US$ 326 
            
                
                        US$ 814 
                                        US$ 1628 
                                        US$ 4884 
                                        US$ 12210 
                            
 For more details, please contact local distributors!
ACTIVITY TEST
 
                                Interleukin 34 (IL-34) is a protein belonging to a group of cytokines called interleukins. IL-34 increases growth or survival of immune cells known as monocytes; it elicits its activity by binding the Colony stimulating factor 1 receptor. To explore the effect of IL-34 induction of bone marrow cells differentiation into macrophages,1×106 density of bone marrow cells were cultured with different concentration of recombinant mouse IL-34 for 7days, every three day changed with fresh culture. Setting the blank well without IL-34 as the control well. After 7days later, bone marrow cells culture with 1ug/ml IL-34 were significantiy differentiation into macrophages. The result observed by inverted microscope was shown on Figure1. Ink phagocytosis test shows ,after stimulated by IL-34, most of cells have phagocytosis function. The results were shown on Figure2.
 
                                Figure2. Ink phagocytosis test.
USAGE
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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| Magazine | Citations | 
| J Int Med Res. | Increased Serum Interleukin-34 in Patients with Coronary Artery Disease PubMed: 23206468 | 
| Transplantation | IL-34 inhibits acute rejection of rat liver transplantation by inducing Kupffer cell M2 polarization Pubmed:29570162 | 
| cyberleninka | КЛИНИКО-ЭПИДЕМИОЛОГИЧЕСКАЯ ХАРАКТЕРИСТИКА И ОСОБЕННОСТИ БАЛЛАНСА ЦИТОКИНОВ ПРИ КЛЕЩЕВОМ ЭНЦЕФАЛИТЕ В … | 
| Revista da Associacao Medica Brasileira | A comparison of IL-17 and IL-34 concentrations in the cerebrospinal fluid of patients with acute inflammatory demyelinating neuropathy and chronic … | 
| Rev Assoc Med Bras | A comparison of IL-17 and IL-34 concentrations in the cerebrospinal fluid of patients with acute inflammatory demyelinating neuropathy and chronic?¡ 33295414 | 
| Catalog No. | Related products for research use of Mus musculus (Mouse) Organism species | Applications (RESEARCH USE ONLY!) | 
| RPC007Mu02 | Recombinant Interleukin 34 (IL34) | Positive Control; Immunogen; SDS-PAGE; WB. | 
| APC007Mu61 | Active Interleukin 34 (IL34) | Cell culture; Activity Assays. | 
| EPC007Mu61 | Eukaryotic Interleukin 34 (IL34) | Positive Control; Immunogen; SDS-PAGE; WB. | 
| RPC007Mu01 | Recombinant Interleukin 34 (IL34) | Positive Control; Immunogen; SDS-PAGE; WB. | 
| APC007Mu01 | Active Interleukin 34 (IL34) | Cell culture; Activity Assays. | 
| PAC007Mu01 | Polyclonal Antibody to Interleukin 34 (IL34) | WB | 
| PAC007Mu02 | Polyclonal Antibody to Interleukin 34 (IL34) | WB; IHC; ICC; IP. | 
| LAC007Mu71 | Biotin-Linked Polyclonal Antibody to Interleukin 34 (IL34) | WB; IHC; ICC. | 
| MAC007Mu21 | Monoclonal Antibody to Interleukin 34 (IL34) | WB; IHC; ICC; IP. | 
| MEC007Mu | Mini Samples ELISA Kit for Interleukin 34 (IL34) | Enzyme-linked immunosorbent assay for Antigen Detection. | 
| SEC007Mu | ELISA Kit for Interleukin 34 (IL34) | Enzyme-linked immunosorbent assay for Antigen Detection. | 
| SCC007Mu | CLIA Kit for Interleukin 34 (IL34) | Chemiluminescent immunoassay for Antigen Detection. | 
| LMC007Mu | Multiplex Assay Kit for Interleukin 34 (IL34) ,etc. by FLIA (Flow Luminescence Immunoassay) | FLIA Kit for Antigen Detection. | 
 
         
 
                            

 
     
