Interleukin 18 (IL18)

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IGIF; IL-1g; IL1F4; IL1-F4; Interferon-Gamma-Inducing Factor; Interleukin-1 Family Member 4; Iboctadekin; Interleukin-1 Gamma

Interleukin 18 (IL18)

IL-18 is a 18 kDa novel cytokine which is identified as a costimulatory factor for production of interferon-γ (IFN- γ ) in response to toxic shock. It shares functional similarities with IL-12. IL-18 is synthesized as a precursor 24 kDa molecule without a signal peptide and must be cleaved to produce an active molecule. IL-1 ß converting enzyme (ICE, Caspase-1) cleaves pro-IL-18 at aspartic acid in the P1 position, producing the mature, bioactive peptide that is readily released from the cells. It has been reported that IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon.Apart from its physiological role, IL-18 is also able to induce severe inflammatory reactions, which suggests its role in certain inflammatory disorders.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA064Hu01 Recombinant Interleukin 18 (IL18) Positive Control; Immunogen; SDS-PAGE; WB.
APA064Hu01 Active Interleukin 18 (IL18) Cell culture; Activity Assays.
EPA064Hu61 Eukaryotic Interleukin 18 (IL18) Positive Control; Immunogen; SDS-PAGE; WB.
RPA064Hu02 Recombinant Interleukin 18 (IL18) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA064Hu01 Polyclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
LAA064Hu71 Biotin-Linked Polyclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC.
LAA064Hu81 FITC-Linked Polyclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IF.
MAA064Hu21 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC
MAA064Hu22 Monoclonal Antibody to Interleukin 18 (IL18) WB,IHC
MAA064Hu23 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
MAA064Hu24 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
MAA064Hu25 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
MAA064Hu27 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
MAA064Hu29 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
MAA064Hu26 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
MAA064Hu28 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
Assay Kits SEA064Hu ELISA Kit for Interleukin 18 (IL18) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA064Hu CLIA Kit for Interleukin 18 (IL18) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA064Mu01 Recombinant Interleukin 18 (IL18) Positive Control; Immunogen; SDS-PAGE; WB.
RPA064Mu02 Recombinant Interleukin 18 (IL18) Positive Control; Immunogen; SDS-PAGE; WB.
APA064Mu01 Active Interleukin 18 (IL18) Cell culture; Activity Assays.
EPA064Mu61 Eukaryotic Interleukin 18 (IL18) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA064Mu01 Polyclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
LAA064Mu71 Biotin-Linked Polyclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC.
PAA064Mu02 Polyclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
Assay Kits SEA064Mu ELISA Kit for Interleukin 18 (IL18) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA064Ra01 Recombinant Interleukin 18 (IL18) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA064Ra01 Polyclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
LAA064Ra71 Biotin-Linked Polyclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC.
MAA064Ra21 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
MAA064Ra22 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
MAA064Ra23 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
Assay Kits SEA064Ra ELISA Kit for Interleukin 18 (IL18) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA064Ra CLIA Kit for Interleukin 18 (IL18) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Cavia (Guinea pig )

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Interleukin 18 (IL18) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Interleukin 18 (IL18) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Interleukin 18 (IL18) Polyclonal Antibody Customized Service Offer
Assay Kits SEA064Gu ELISA Kit for Interleukin 18 (IL18) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA064Rb01 Recombinant Interleukin 18 (IL18) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA064Rb51 Polyclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
MAA064Rb21 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
MAA064Rb22 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
MAA064Rb23 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
MAA064Rb24 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
MAA064Rb25 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
Assay Kits SEA064Rb ELISA Kit for Interleukin 18 (IL18) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA064Ca01 Recombinant Interleukin 18 (IL18) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA064Ca01 Polyclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
MAA064Ca21 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
Assay Kits SEA064Ca ELISA Kit for Interleukin 18 (IL18) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA064Po01 Recombinant Interleukin 18 (IL18) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA064Po01 Polyclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
MAA064Po21 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
Assay Kits SEA064Po ELISA Kit for Interleukin 18 (IL18) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA064Bo01 Recombinant Interleukin 18 (IL18) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA064Bo01 Polyclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
MAA064Bo21 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
MAA064Bo24 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
LAA064Bo72 Biotin-Linked Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC.
Assay Kits SEA064Bo ELISA Kit for Interleukin 18 (IL18) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Capra hircus; Caprine (Goat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA064Cp01 Recombinant Interleukin 18 (IL18) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA064Cp01 Polyclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Interleukin 18 (IL18) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 18 (IL18) ELISA Kit Customized Service Offer

Organism species: Equus caballus; Equine (Horse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA064Eq01 Recombinant Interleukin 18 (IL18) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA064Eq01 Polyclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
MAA064Eq21 Monoclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
Assay Kits SEA064Eq ELISA Kit for Interleukin 18 (IL18) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA064Ga01 Recombinant Interleukin 18 (IL18) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA064Ga01 Polyclonal Antibody to Interleukin 18 (IL18) WB; IHC; ICC; IP.
Assay Kits SEA064Ga ELISA Kit for Interleukin 18 (IL18) Enzyme-linked immunosorbent assay for Antigen Detection.
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  3. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
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