Active Interleukin 11 (IL11)
AGIF; Adipogenesis Inhibitory Factor; Oprelvekin
- Product No.APA057Hu61
- Organism SpeciesHomo sapiens (Human) Same name, Different species.
- Buffer FormulationPBS, pH7.4, containing 5% Trehalose.
- Traits Freeze-dried powder
- Purity> 95%
- Isoelectric Point11.7
- ApplicationsCell culture; Activity Assays.
- DownloadInstruction Manual
- UOM 10µg50µg 200µg 1mg 5mg
- FOB
US$ 328
For more details, please contact local distributors! US$ 821 US$ 1642 US$ 4926 US$ 12315
ACTIVITY TEST

Interleukin 11 (IL-11) is a multifunctional cytokine. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute phase proteins, modulate antigen-antibody responses and participate in the regulation of bone cell proliferation and differentiation. Besides, IL-11 has been proved to promote cell proliferation of TF-1 cells. 2x104 TF-1 cells were seeded into a well of 96-well plates and allowed to attach, replaced with various concentrations of recombinant human TRAIL. After incubated for 72 hours, the 96-well plate was read at OD450 nm. The result was shown in Figure1. It was obvious that recombinant IL-11 protein significantly increased cell viability of TF-1 cells. Its EC50 is 0.5677μg/mL.
USAGE
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Magazine | Citations |
Molecular Medicine Reports | Regulatory effect of chemerin and therapeutic efficacy of chemerin‑9 in pancreatogenic diabetes mellitus Pubmed: 31922216 |
Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
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