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Monoclonal Antibody to Chymase 1, Mast Cell (CMA1)

CYH; CYM; Alpha-chymase; Mast cell protease I

  • Product No.MAG515Ra21
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceMonoclonal antibody preparation
  • HostMouse
  • Potency (Clone Number)n/a
  • Ig Isotype IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration1mg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IHC; ICC; IP.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 120  US$ 280  US$ 400  US$ 1000  US$ 4000 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against CMA1. It has been selected for its ability to recognize CMA1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Pathobiology Anti-Angiotensin and Hypoglycemic Treatments Suppress Liver Metastasis of Colon Cancer Cells Karger: 000330169
Clinical and Experimental Metastasis Diabetes-associated angiotensin activation enhances liver metastasis of colon cancer PubMed: 22552372
Mediators of Inflammation Mediators of Mast Cells in Bullous Pemphigoid and Dermatitis Herpetiformis Pubmed:25400334
Neurogastroenterology & Motility Peritoneal mast cell degranulation and gastrointestinal recovery in patients undergoing colorectal surgery Pubmed:25677271
IJC Metab Endocr The autocrine role of tryptase in pressure overload-induced mast cell activation, chymase release and cardiac fibrosis PubMed: 26722642
Journal of Neuroinflammation Oral sensitization to whey proteins induces age-and sex-dependent behavioral abnormality and neuroinflammatory responses in a mouse model of food … Pubmed:29685134
Revista do Instituto de Medicina Tropical de São Paulo Vasoactive intestinal peptide degradation might influence Interleukin-17 expression in cardiac chagasic patients Pubmed: 30365640
Science Advances Platelets trigger perivascular mast cell degranulation to cause inflammatory responses and tissue injury Pubmed: 32206714
Immunity Inflammation and Disease Disruption in the balance between apolipoprotein A‐I and mast cell chymase in chronic hypersensitivity pneumonitis Pubmed: 33016012
Microbiol Spectr Mast Cell-Derived Proteases Induce Endothelial Permeability and Vascular Damage in Severe Fever with Thrombocytopenia Syndrome Pubmed:35612327
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
RPG515Ra01 Recombinant Chymase 1, Mast Cell (CMA1) Positive Control; Immunogen; SDS-PAGE; WB.
PAG515Ra01 Polyclonal Antibody to Chymase 1, Mast Cell (CMA1) WB; IHC; ICC; IP.
MAG515Ra21 Monoclonal Antibody to Chymase 1, Mast Cell (CMA1) WB; IHC; ICC; IP.
SEG515Ra ELISA Kit for Chymase 1, Mast Cell (CMA1) Enzyme-linked immunosorbent assay for Antigen Detection.
LMG515Ra Multiplex Assay Kit for Chymase 1, Mast Cell (CMA1) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.