FITC-Linked Polyclonal Antibody to Glutamine synthetase (GS)

GLNS; GLUL; Glutamate-Ammonia Ligase; Glutamate decarboxylase

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against GS. It has been selected for its ability to recognize GS in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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INCREMENT SERVICES

Magazine Citations
The FASEB Journal Cargo proteins of plasma astrocyte-derived exosomes in Alzheimer’s disease pubmed:27511944
Annals of Neurology  High complement levels in astrocyte‐derived exosomes of Alzheimer disease Pubmed:29406582
Journal of Neuroscience Sex differences in the glutamate signaling pathway in juvenile rats Pubmed:28861894
FASEB Journal Deficient neurotrophic factors of CSPG4-type neural cell exosomes in Alzheimer disease Pubmed:29924942
Hepatology Research Glutamine synthetase promotes tumor invasion in hepatocellular carcinoma through mediating epithelial–mesenchymal transition Pubmed: 31652385
FASEB JOURNAL Traumatic brain injury increases plasma astrocyte‐derived exosome levels of neurotoxic complement proteins Pubmed: 31916313
Translational Psychiatry Decreased mitochondrial electron transport proteins and increased complement mediators in plasma neural-derived exosomes of early psychosis Pubmed: 33106473
Drug Repurposing of Asparaginase and Vitamin C Targeting Glutamine Synthetase Improves Anticancer Effect in Metastatic Castration-resistant Prostate …
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