Recombinant Heparanase (HPSE)

HPA; HPR1; HPSE1; HSE1; Endo-glucoronidase;

  • Product No.RPA711Ra01
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationLysosome membrane; Peripheral membrane protein. Secreted. Nucle
  • Predicted Molecular Mass20.9kDa
  • Accurate Molecular Mass20.87kDa(Analysis of differences refer to the manual)
  • Residues & TagsArg40~Pro188 (Accession # Q71RP1) with
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point8.7
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 192  US$ 480  US$ 960  US$ 2880  US$ 7200 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in PBS or others.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Plos one PG545, a Heparan Sulfate Mimetic, Reduces Heparanase Expression In Vivo, Blocks Spontaneous Metastases and Enhances Overall Survival in the 4T1 Breast Carcinoma Model Plosone: Source
Journal of Medical Science Assessment of heparanase and heparin-binding growth and angiogenesis factors in the uterine cavity ? uid in women with impaired reproduction Nowinylekarskie:Source
Int J Clin Exp Pathol Unfractionated heparin attenuates intestinal injury in mouse model of sepsis by inhibiting heparanase PubMed: 26191183
Tumour Biology PI-88 inhibits postoperative recurrence of hepatocellular carcinoma via disrupting the surge of heparanase after liver resection PubMed: 26415733
Journal of Medical Science Assessment of heparanase and heparin-binding growth and angiogenesis factors in the uterine cavity fluid in women with impaired reproduction article:84
Renal Failure Plasma heparanase is associated with blood glucose levels but not urinary microalbumin excretion in type 2 diabetic nephropathy at the early stage pubmed:28994624
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
RPA711Ra01 Recombinant Heparanase (HPSE) Positive Control; Immunogen; SDS-PAGE; WB.
PAA711Ra01 Polyclonal Antibody to Heparanase (HPSE) WB; IHC
LAA711Ra71 Biotin-Linked Polyclonal Antibody to Heparanase (HPSE) WB; IHC; ICC.
MAA711Ra21 Monoclonal Antibody to Heparanase (HPSE) WB; ICC/IF
MAA711Ra25 Monoclonal Antibody to Heparanase (HPSE) WB
MAA711Ra26 Monoclonal Antibody to Heparanase (HPSE) WB
MAA711Ra27 Monoclonal Antibody to Heparanase (HPSE) WB
MAA711Ra28 Monoclonal Antibody to Heparanase (HPSE) WB
MAA711Ra24 Monoclonal Antibody to Heparanase (HPSE) WB
MAA711Ra22 Monoclonal Antibody to Heparanase (HPSE) WB
MAA711Ra23 Monoclonal Antibody to Heparanase (HPSE) WB
SEA711Ra ELISA Kit for Heparanase (HPSE) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA711Ra Multiplex Assay Kit for Heparanase (HPSE) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.