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Recombinant Amyloid Precursor Protein (APP)

AAA; ABeta; ABPP; AD1; APPI; CVAP; PN2; CTFgamma; Peptidase Nexin-II Alzheimer Disease; Peptidase Nexin-II; Amyloid Beta(A4)Precursor Protein

  • Product No.RPB020Ra01
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane
  • Predicted Molecular Mass60.0kDa
  • Accurate Molecular Mass60kDa(Analysis of differences refer to the manual)
  • Residues & TagsLeu18~Val286 with N-terminal His and GST Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point3.9
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 180  US$ 450  US$ 900  US$ 2700  US$ 6750 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Neurochemistry International Bilobalide regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathway ScienceDirect: S0197018611001641
Neuroscience Substitution of membrane cholesterol with β-sitosterol promotes nonamyloidogenic cleavage of endogenous amyloid precursor protein Pubmed: 23707801
OncoImmunology PROOF COVER SHEET
台湾农业研究 (台灣農業研究67 (4): 355-364) 香菇柄水萃物改善糖尿病降低阿茲海默氏症罹病風險初探
Neurotoxicology Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice Pubmed: 32522471
Metab Brain Dis Probiotics ameliorates LPS induced neuroinflammation injury on Aβ 1–42, APP, γ-β secretase and BDNF levels in maternal gut microbiota and fetal … Pubmed:35312928
Exp Gerontol The positive impact of 12 weeks of dance and balance training on the circulating amyloid precursor protein and serotonin concentration as well as physical and … Pubmed:35217193
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
RPB020Ra01 Recombinant Amyloid Precursor Protein (APP) Positive Control; Immunogen; SDS-PAGE; WB.
PAB020Ra01 Polyclonal Antibody to Amyloid Precursor Protein (APP) Testing in progress
MAB020Ra21 Monoclonal Antibody to Amyloid Precursor Protein (APP) WB; IHC; ICC; IP.
WEB020Ra Wide-range ELISA Kit for Amyloid Precursor Protein (APP) Enzyme-linked immunosorbent assay for Antigen Detection.
SEB020Ra ELISA Kit for Amyloid Precursor Protein (APP) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB020Ra Multiplex Assay Kit for Amyloid Precursor Protein (APP) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
CMB020Ra Multiplex Assay Kit for Amyloid Precursor Protein (APP) ,etc. by CBA (Cytometric Bead Array) FLIA Kit for Antigen Detection.