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Recombinant Semaphorin 4D (SEMA4D)

CD100; A8; BB18; GR3; M-Sema G; M-Sema-G; SEMAJ; Coll-4; Sema Domain,Immunoglobulin Domain(Ig),Transmembrane Domain(TM)and Short Cytoplasmic Domain 4D

  • Product No.RPB430Mu01
  • Organism SpeciesMus musculus (Mouse) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane, Chromosome
  • Predicted Molecular Mass16.4kDa
  • Accurate Molecular Mass16kDa(Analysis of differences refer to the manual)
  • Residues & TagsPhe502~Ser636 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point8.1
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 179  US$ 448  US$ 896  US$ 2688  US$ 6720 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Expert Opin Ther Targets. Circulating semaphorin-4D and plexin-B1 levels in postmenopausal women with low bone mass: the 3-month effect of zoledronic acid, denosumab or teriparatide treatment Pubmed:25395071
Obesity (Silver Spring). Genome-wide analysis identifies an african-specific variant in SEMA4D associated with body mass index. pubmed:28296344
Clinical Lymphoma, Myeloma & Leukemia A Revised Staging System for Waldenström's Macroglobulinemia 10.1016/j.clml.2017.07.146
Clinical Lymphoma, Myeloma & Leukemia Extramedullary Multiple Myeloma: Clinical Features and Prognosis in Argentina 10.1016/j.clml.2017.07.144
Blood Cancer Journal Semaphorin 4D correlates with increased bone resorption, hypercalcemia, and disease stage in newly diagnosed patients with multiple myeloma Pubmed:29748532
Analytical Biochemistry A high-sensitivity enzyme immunoassay for the quantification of soluble human semaphorin 4D in plasma Pubmed: 30879960
Journal of Allergy and Clinical Immunology-In Practice Pathological and therapeutic implications of eosinophil-derived semaphorin 4D in eosinophilic chronic rhinosinusitis Pubmed: 32035658
Catalog No. Related products for research use of Mus musculus (Mouse) Organism species Applications (RESEARCH USE ONLY!)
RPB430Mu01 Recombinant Semaphorin 4D (SEMA4D) Positive Control; Immunogen; SDS-PAGE; WB.
RPB430Mu02 Recombinant Semaphorin 4D (SEMA4D) Positive Control; Immunogen; SDS-PAGE; WB.
PAB430Mu02 Polyclonal Antibody to Semaphorin 4D (SEMA4D) WB
PAB430Mu01 Polyclonal Antibody to Semaphorin 4D (SEMA4D) WB; ICC/IF
SEB430Mu ELISA Kit for Semaphorin 4D (SEMA4D) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB430Mu Multiplex Assay Kit for Semaphorin 4D (SEMA4D) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
CMB430Mu Multiplex Assay Kit for Semaphorin 4D (SEMA4D) ,etc. by CBA (Cytometric Bead Array) FLIA Kit for Antigen Detection.