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Recombinant Complement Factor I (CFI)

CF-I; C3b-INA; FI; IF; KAF; Factor I; Konglutinogen-Activating Factor; C3b-Inactivator; C3B/C4B inactivator

  • Product No.RPB978Mu01
  • Organism SpeciesMus musculus (Mouse) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted, Extracellular matrix
  • Predicted Molecular Mass31.3kDa
  • Accurate Molecular Mass31kDa(Analysis of differences refer to the manual)
  • Residues & TagsArg358~Val603 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point8.4
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 191  US$ 478  US$ 956  US$ 2868  US$ 7170 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
J Thromb Haemost A case report of thrombotic microangiopathy without renal involvement carrying two novel mutations in complement-regulator genes PubMed: 26613809
Pediatr Int Atypical hemolytic uremic syndrome: Korean pediatric series PubMed: 25443527
United States Patent Application  NOVEL ASSAY y2016:139118
Researchgate Compliment factor i bioassay US20170285024
PLoS One A monoclonal antibody targeting amyloid β (Aβ) restores complement factor I bioactivity: Potential implications in age-related macular degeneration and … Pubmed:29782502
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE The importance of sialic acid, pH and ion concentration on the interaction of uromodulin and complement factor H 33788378
Catalog No. Related products for research use of Mus musculus (Mouse) Organism species Applications (RESEARCH USE ONLY!)
RPB978Mu01 Recombinant Complement Factor I (CFI) Positive Control; Immunogen; SDS-PAGE; WB.
PAB978Mu01 Polyclonal Antibody to Complement Factor I (CFI) WB; IHC; ICC; IP.