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Recombinant Vanin 1 (VNN1)

Pantetheinase; Pantetheine hydrolase; Tiff66; Vascular non-inflammatory molecule 1

  • Product No.RPC598Mu01
  • Organism SpeciesMus musculus (Mouse) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane
  • Predicted Molecular Mass13.8kDa
  • Accurate Molecular Mass14kDa(Analysis of differences refer to the manual)
  • Residues & TagsVal390~Ile503 (Accession # Q9Z0K8) with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 97%
  • Isoelectric Point7.05
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 160  US$ 400  US$ 800  US$ 2400  US$ 6000 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Toxicology Vanin-1; a potential biomarker for nephrotoxicant-induced renal injury ScienceDirect: S0300483X11003234
Journal of Pharmacology and Experimental Therapeutics Urinary vanin-1 as a novel biomarker for early detection of drug-induced acute kidney injury Aspet: 192807
J Pharmacol Exp Ther Urinary vanin-1 as a novel biomarker for early detection of drug-induced acute kidney injury. PubMed: 22399813
Journal of Applied Toxicology Early detection of renal injury using urinary vanin-1 in rats with experimental colitis PubMed: 23307618
Iranian Journal of Health and Physical Activity Effects of Exercise and Ferula Gummosa on Apelin of Cardiac and Kidney Tissues in L-NAME induced Hypertension in Rats Jm.um: Source
Platelets Value of vanin-1 assessment in adult patients with primary immune thrombocytopenia Pubmed: 23534352
Journal of Applied Toxicology Early detection of renal injury using urinary vanin-1 in rats with experimental colitis. Pubmed: 23307618
Diabetes &amp; Vascular Disease Research Urinary Kim-1 is a sensitive biomarker for the early stage of diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty rats Sagepub:Source
Food Chem Toxicol. The effect of activated charcoal on adenine-induced chronic renal failure in rats Pubmed:24412558
Hypertension Research Early urinary biomarkers for renal tubular damage in spontaneously hypertensive rats on a high salt intake PubMed: 26376947
Inflammation Citrate Attenuates Adenine-Induced Chronic Renal Failure in Rats by Modulating the Th17/Treg Cell Balance PubMed: 26253296
Toxicology Early prediction of cisplatin-induced nephrotoxicity by urinary vanin-1 in patients with urothelial carcinoma Pubmed:27317936
J Biomed Mater Res A Nanosized titanium dioxide resulted in the activation of TGF-β/Smads/p38MAPK pathway in renal inflammation and fibration of mice Pubmed:26850371
APMIS Citrate attenuates vascular calcification in chronic renal failure rats. pubmed:28332248
Clin Exp Pharmacol Physiol. Early urinary biomarkers of renal tubular damage by a high-salt intake independent of blood pressure in normotensive rats. pubmed:29027259
Cellular Physiology and Biochemistry Gum Acacia Improves Renal Function and Ameliorates Systemic Inflammation, Oxidative and Nitrosative Stress in Streptozotocin-Induced Diabetes in Rats … Pubmed:29550811
International Journal of Molecular Sciences Vanin-1 in Renal Pelvic Urine Reflects Kidney Injury in a Rat Model of Hydronephrosis Pubmed: 30332759
International Journal of Molecular Sciences Involvement of Vanin-1 in Ameliorating Effect of Oxidative Renal Tubular Injury in Dahl-Salt Sensitive Rats Pubmed: 31514290
The Journal of Clinical Hypertension homepage Urinary vanin‐1 associated with chronic kidney disease in hypertensive patients: A pilot study Pubmed: 32869948
J Clin Hypertens Association of urinary vanin©\1 with kidney function decline in hypertensive patients 34029440
Plasma vanin-1 as a novel biomarker of sepsis for trauma patients: a prospective multicenter cohort study 33624223
Catalog No. Related products for research use of Mus musculus (Mouse) Organism species Applications (RESEARCH USE ONLY!)
RPC598Mu01 Recombinant Vanin 1 (VNN1) Positive Control; Immunogen; SDS-PAGE; WB.
PAC598Mu01 Polyclonal Antibody to Vanin 1 (VNN1) WB; IHC; ICC; IP.
LAC598Mu71 Biotin-Linked Polyclonal Antibody to Vanin 1 (VNN1) WB; IHC; ICC.
SEC598Mu ELISA Kit for Vanin 1 (VNN1) Enzyme-linked immunosorbent assay for Antigen Detection.
LMC598Mu Multiplex Assay Kit for Vanin 1 (VNN1) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.