Recombinant Uncoupling Protein 1, Mitochondrial (UCP1)
SLC25A7; UCP; Thermogenin; Solute carrier family 25 member 7
- Product No.RPF557Mu01
 - Organism SpeciesMus musculus (Mouse) Same name, Different species.
 - SourceProkaryotic expression
 - HostE.coli
 - Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
 - Subcellular LocationMembrane
 - Predicted Molecular Mass14.3kDa
 - Accurate Molecular Mass13kDa(Analysis of differences refer to the manual)
 - Residues & TagsPro179~Leu296 with N-terminal His Tag
 - Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
 - Traits Freeze-dried powder
 - Purity> 97%
 - Isoelectric Point7.7
 - 
                        Applications
                        Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein. - DownloadInstruction Manual
 - UOM 10µg50µg 200µg 1mg 5mg
 - FOB
    
                                    US$ 176 
            
                
                        US$ 440 
                                        US$ 880 
                                        US$ 2640 
                                        US$ 6600 
                            
For more details, please contact local distributors! 
SEQUENCE
                                
                            USAGE
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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INCREMENT SERVICES
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                        Buffer
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                        Endotoxin Removal Kit II
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                        Real Time PCR Experimental Service
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                        Spike RBD Protein (S-RBD)
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                        Protein G
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                        Protein A
                                     
| Magazine | Citations | 
| Stem Cells | FM19G11 Favors Spinal Cord Injury Regeneration and Stem Cell Self-Renewal by Mitochondrial Uncoupling and Glucose Metabolism Induction PubMed: 22865656 | 
| Diabetes. | Inorganic nitrate promotes the browning of white adipose tissue through the nitrate-nitrite-nitric oxide pathway Pubmed:25249574 | 
| Journal of Cachexia, Sarcopenia and Muscle | Muscle wasting and adipose tissue browning in infantile nephropathic cystinosis Doi: 10.1002 | 
| FASEB J | Single-cell transcriptomics and functional target validation of brown adipocytes show their complex roles in metabolic homeostasis PubMed: 26304220 | 
| FASEB JOURNAL | Irradiation of carotid baroreceptor with low‐intensity pulsed ultrasound exerts different metabolic protection in perirenal, epididymal white adipose tissue and … Pubmed: 32954574 | 
| Brown and beige adipose tissue regulate systemic metabolism to resist diet-induced obesity through metabolite signals in an inter-organ signaling axis | |
| Science reports | All-trans-retinoic acid ameliorates atherosclerosis, promotes perivascular adipose tissue browning, and increases adiponectin production in Apo-E mice 33627760 | 
| Nature Communications | Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis 33772024 | 
        
                            
